Prostaglandin E2

Also known as: Dinoprostone, PGE2, Cervidil, Prepidil, Propess, Prostin E2, (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, (-)-Prostaglandin E2, L-PGE2

Prostaglandin E2 (CAS 363-24-6) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C20H32O5 and a molecular weight of 352.465 g/mol. Key properties include a melting point of 66-68 °C, a boiling point of 530.1±50.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 288.5±26.6 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed and H360 — May damage fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 363-24-6
Jingsj CID: J-42136-6
Molecular Formula: C₂₀H₃₂O₅
Molecular Weight: 352.465 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	66-68 °C
Boiling Point	530.1±50.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	288.5±26.6 °C
Exact Mass	352.224976
PSA	94.83000
LogP	1.88
Vapor Pressure	0.0±3.2 mmHg at 25°C
Refractive Index	1.561
Additional Property	insoluble

GHS Safety & Compliance

Irritant / Health HazardSignal word: Danger

H302 — Harmful if swallowed
H360 — May damage fertility or the unborn child

Activity & Biological Data

Target	EP2 Receptor Human Endogenous Metabolite
Additional Information	[1]. Chouaib S, et al. The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes. J Immunol. 1984 Apr;132(4):1851-7. [2]. Fernandez-Repollet E, et al. In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. J Histochem Cytochem. 1982 May;30(5):466-70. [3]. Haylor J, et al. Renal vasodilator activity of prostaglandin E2 in the rat anaesthetized with pentobarbitone. Br J Pharmacol. 1982 May;76(1):131-7.

Target

EP2 Receptor Human Endogenous Metabolite

Additional Information

[1]. Chouaib S, et al. The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes. J Immunol. 1984 Apr;132(4):1851-7. [2]. Fernandez-Repollet E, et al. In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. J Histochem Cytochem. 1982 May;30(5):466-70. [3]. Haylor J, et al. Renal vasodilator activity of prostaglandin E2 in the rat anaesthetized with pentobarbitone. Br J Pharmacol. 1982 May;76(1):131-7.

Frequently Asked Questions

What is the CAS number of Prostaglandin E2?

The CAS number of Prostaglandin E2 is 363-24-6.

What are the molecular formula and molecular weight of Prostaglandin E2?

Prostaglandin E2 has molecular formula C20H32O5 and molecular weight 352.465 g/mol.

Is Prostaglandin E2 hazardous?

Prostaglandin E2 has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H360 — May damage fertility or the unborn child.

What are the upstream and downstream products of Prostaglandin E2?

For Prostaglandin E2, Upstream Products: cis-3,5-Diacetoxy-1-cyclopentene, Cyclopentadiene, (3aS,6aS)-2,2-Dimethyl-3a,6a-dihydro-4H-cyclopenta[d][1,3]dioxol-4-one; Downstream Products: Dinoprost, Prostaglandin F2β, Prostaglandin A2.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Prostaglandin E2 (CAS 363-24-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-42136-6 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.