N-Formyl-L-methionyl-L-leucyl-L-phenylalanine

Also known as: N-Formyl-Met-Leu-Phe, fMLF, Chemotactic peptide, For-Met-Leu-Phe-OH, N-Formylmethionine leucyl-phenylalanine, N-Formyl-L-methionyl-L-leucyl-L-phenylalanine, Formyl-Met-Leu-Phe-OH, MFCD00012901

N-Formyl-L-methionyl-L-leucyl-L-phenylalanine (CAS 59880-97-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C21H31N3O5S and a molecular weight of 437.553 g/mol. Key properties include a melting point of 271-274 °C(lit.), a boiling point of 783.5±60.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 427.6±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 59880-97-6
Jingsj CID: J-4121-4
Molecular Formula: C₂₁H₃₁N₃O₅S
Molecular Weight: 437.553 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	271-274 °C(lit.)
Boiling Point	783.5±60.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	427.6±32.9 °C
Exact Mass	437.198456
PSA	149.90000
LogP	3.13
Vapor Pressure	0.0±2.9 mmHg at 25°C
Refractive Index	1.551
Storage Conditions	2-8℃
Additional Property	DMF: 50 mg/mL, clear, colorless

Activity & Biological Data

Target	TNF-alpha[1]
Additional Information	[1]. Shin MK, et al. N-formyl-methionyl-leucyl-phenylalanine (fMLP) promotes osteoblast differentiation via the N-formyl peptide receptor 1-mediated signaling pathway in human mesenchymal stem cells from bone marrow. J Biol Chem. 2011 May 13;286(19):17133-43. [2]. Chen LY, et al. Synergistic induction of inflammation by bacterial products lipopolysaccharide and fMLP: an important microbial pathogenic mechanism. J Immunol. 2009 Feb 15;182(4):2518-24. [3]. Hetland G, et al. Chemotaxins C5a and fMLP induce release of calprotectin (leucocyte L1 protein) from polymorphonuclear cells in vitro. Mol Pathol. 1998 Jun;51(3):143-8.

Target

TNF-alpha[1]

Additional Information

[1]. Shin MK, et al. N-formyl-methionyl-leucyl-phenylalanine (fMLP) promotes osteoblast differentiation via the N-formyl peptide receptor 1-mediated signaling pathway in human mesenchymal stem cells from bone marrow. J Biol Chem. 2011 May 13;286(19):17133-43. [2]. Chen LY, et al. Synergistic induction of inflammation by bacterial products lipopolysaccharide and fMLP: an important microbial pathogenic mechanism. J Immunol. 2009 Feb 15;182(4):2518-24. [3]. Hetland G, et al. Chemotaxins C5a and fMLP induce release of calprotectin (leucocyte L1 protein) from polymorphonuclear cells in vitro. Mol Pathol. 1998 Jun;51(3):143-8.

Customs & Trade Information

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of N-Formyl-L-methionyl-L-leucyl-L-phenylalanine?

The CAS number of N-Formyl-L-methionyl-L-leucyl-L-phenylalanine is 59880-97-6.

What are the molecular formula and molecular weight of N-Formyl-L-methionyl-L-leucyl-L-phenylalanine?

N-Formyl-L-methionyl-L-leucyl-L-phenylalanine has molecular formula C21H31N3O5S and molecular weight 437.553 g/mol.

What are the upstream and downstream products of N-Formyl-L-methionyl-L-leucyl-L-phenylalanine?

For N-Formyl-L-methionyl-L-leucyl-L-phenylalanine, Upstream Products: Boc-Leu-OSu, L-Phenylalanine benzyl ester p-toluenesulfonate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "N-Formyl-L-methionyl-L-leucyl-L-phenylalanine (CAS 59880-97-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-4121-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.