4-hydroxyantipyrine
Also known as: 1,2-dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, 1,5-Dimethyl-2-phenyl-4-hydroxy-4-pyrazoline-3-one, 1-Phenyl-2,3-dimethyl-4-hydroxy-5-pyrazolone, 1-phenyl-2,3-dimethyl-4-hydroxy-pyrazoline-5-one, 2,3-Dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3-one, 4-Hydroxy-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, 4-Hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one, 4-Hydroxy-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, 4-hydroxy-1,5-dimethyl-2-phenyl-1,2-dihydro-3h-pyrazol-3-one, 4-hydroxy-1,5-dimethyl-2-phenyl-pyrazol-3-one, 4-hydroxy-1,5-dimethyl-2-phenylpyrazol-3-one, Antipyrine,4-hydroxy, MFCD00003143, NSC 174055, Prestwick_270, hydroxy-4 antipyrine
4-hydroxyantipyrine (CAS 1672-63-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C11H12N2O2 and a molecular weight of 204.22500 g/mol. Key properties include a melting point of 184-186ºC(lit.), a boiling point of 314.3ºC at 760mmHg, a density of 1.294g/cm3 and a flash point of 143.9ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1672-63-5
- Jingsj CID
- J-40256-2
- Molecular Formula
- C11H12N2O2
- Molecular Weight
- 204.22500 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 184-186ºC(lit.) |
|---|---|
| Boiling Point | 314.3ºC at 760mmHg |
| Density | 1.294g/cm3 |
| Flash Point | 143.9ºC |
| Exact Mass | 204.09000 |
| PSA | 47.16000 |
| LogP | 1.19000 |
| Vapor Pressure | 0.000199mmHg at 25°C |
| Refractive Index | 1.63 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Ohkawa Y, et al. Effects of 4-hydroxyantipyrine and its 4-O-sulfate on antipyrine as biodistribution promoter. Biol Pharm Bull. 2001 May;24(5):529-34. [2]. Ohkawa Y, et al. Application of 4-hydroxyantipyrine and acetaminophen O-sulfate as biodistribution promoter. Biol Pharm Bull. 2001 Dec;24(12):1404-10. |
|---|
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 4-hydroxyantipyrine?
The CAS number of 4-hydroxyantipyrine is 1672-63-5.
What are the molecular formula and molecular weight of 4-hydroxyantipyrine?
4-hydroxyantipyrine has molecular formula C11H12N2O2 and molecular weight 204.22500 g/mol.
Is 4-hydroxyantipyrine hazardous?
4-hydroxyantipyrine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of 4-hydroxyantipyrine?
For 4-hydroxyantipyrine, Upstream Products: 4-Bromoantipyrine, Antipyrine, Aminopyrine; Downstream Products: Oxanilide, Oxalic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "4-hydroxyantipyrine (CAS 1672-63-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-40256-2 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.