Ethoxzolamide
Also known as: 6-ethoxy-2-benzothiazolesulfonamide, 6-Ethoxy-1,3-benzothiazole-2-sulfonamide, 2-Benzothiazolesulfonamide, 6-ethoxy-, Cardrase, Ethamide, Glaucotensil, L-643786, PNU-4191, MFCD00057089
Ethoxzolamide (CAS 452-35-7) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C9H10N2O3S2 and a molecular weight of 258.31700 g/mol. Key properties include a melting point of 190-193ºC(lit.), a boiling point of 464.9ºC at 760mmHg, a density of 1.47g/cm3 and a flash point of 235ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 452-35-7
- Jingsj CID
- J-38918-4
- Molecular Formula
- C9H10N2O3S2
- Molecular Weight
- 258.31700 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 190-193ºC(lit.) |
|---|---|
| Boiling Point | 464.9ºC at 760mmHg |
| Density | 1.47g/cm3 |
| Flash Point | 235ºC |
| Exact Mass | 258.01300 |
| PSA | 118.90000 |
| LogP | 3.12350 |
| Vapor Pressure | 8.05E-09mmHg at 25°C |
| Refractive Index | 1.644 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Ki: 1 nM (carbonic anhydrase)[1] |
|---|---|
| Additional Information | [1]. Maren TH, et al. Relations among IOP reduction, ocular disposition and pharmacology of the carbonic anhydrase inhibitor ethoxzolamide. Exp Eye Res. 1992 Jul;55(1):73-9. [2]. Benjamin K. Johnson, et al. The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits theMycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence. Antimicrob Agents Chemother. 2015 Aug; 59(8): 4436–4445. [3]. Song Gao, et al. Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in plasma and bioequivalent buffers: Applications to absorption, brain distribution, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 1; 0: 54–59. |
Customs & Trade Information
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Frequently Asked Questions
What is the CAS number of Ethoxzolamide?
The CAS number of Ethoxzolamide is 452-35-7.
What are the molecular formula and molecular weight of Ethoxzolamide?
Ethoxzolamide has molecular formula C9H10N2O3S2 and molecular weight 258.31700 g/mol.
Is Ethoxzolamide hazardous?
Ethoxzolamide has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Ethoxzolamide?
For Ethoxzolamide, Downstream Products: 6-hydroxybenzo[d]thiazole-2-carbonitrile, D-Luciferin, L-Luciferin.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Ethoxzolamide (CAS 452-35-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-38918-4 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.