Chlorambucil
Also known as: CB-1348, WR-139013, Leukeran, NSC-3088, 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid, 4-[4-[Bis(2-chloroethyl)amino]phenyl]butanoic acid, Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-, MFCD00021783
Chlorambucil (CAS 305-03-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C14H19Cl2NO2 and a molecular weight of 304.212 g/mol. Key properties include a melting point of 64ºC, a boiling point of 460.1±40.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 232.1±27.3 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 305-03-3
- Jingsj CID
- J-38763-3
- Molecular Formula
- C14H19Cl2NO2
- Molecular Weight
- 304.212 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 64ºC |
|---|---|
| Boiling Point | 460.1±40.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 232.1±27.3 °C |
| Exact Mass | 303.079285 |
| PSA | 40.54000 |
| LogP | 3.10 |
| Vapor Pressure | 0.0±1.2 mmHg at 25°C |
| Refractive Index | 1.570 |
| Stability | Stable, but may be light sensitive. Store cold. Incompatible with strong oxidizing agents. |
| Additional Property | <0.01 g/100 mL at 22 ºC |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
- H350 — May cause cancer
Activity & Biological Data
| Target | DNA Alkylator[1] |
|---|---|
| Additional Information | [1]. Guo JX, et al. Synergistic effects of chlorambucil and TRAIL on apoptosis and proliferation of Raji cells. Eur Rev Med Pharmacol Sci. 2017 Oct;21(20):4703-4710. [2]. Salem FS, et al. Biochemical and pathological studies on the effects of levamisole and chlorambucil on Ehrlich ascites carcinoma-bearing mice. Vet Ital. 2011 Jan-Mar;47(1):89-95. |
Customs & Trade Information
| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Chlorambucil?
The CAS number of Chlorambucil is 305-03-3.
What are the molecular formula and molecular weight of Chlorambucil?
Chlorambucil has molecular formula C14H19Cl2NO2 and molecular weight 304.212 g/mol.
Is Chlorambucil hazardous?
Chlorambucil has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
What are the upstream and downstream products of Chlorambucil?
For Chlorambucil, Downstream Products: Methyl 4-(4-(bis(2-chloroethyl)amino)phenyl)butyrate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Chlorambucil (CAS 305-03-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-38763-3 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.