Tetramethylpyrazine
Also known as: Ligustrazine, 2,3,5,6-Tetramethylpyrazine, Tetramethylpyrazin, FEMA 3237, BS Factor, Pyrazine, 2,3,5,6-tetramethyl-, Tetramethyl-1,4-diazine, Chuanxingzine
Tetramethylpyrazine (CAS 1124-11-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C8H12N2 and a molecular weight of 136.19 g/mol. Key properties include a melting point of 77-80 °C(lit.), a boiling point of 192.7±35.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 71.6±17.6 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1124-11-4
- Jingsj CID
- J-38669-6
- Molecular Formula
- C8H12N2
- Molecular Weight
- 136.19 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 77-80 °C(lit.) |
|---|---|
| Boiling Point | 192.7±35.0 °C at 760 mmHg |
| Density | 1.0±0.1 g/cm3 |
| Flash Point | 71.6±17.6 °C |
| Exact Mass | 136.100052 |
| PSA | 25.78000 |
| LogP | 1.56 |
| Vapor Pressure | 0.7±0.4 mmHg at 25°C |
| Refractive Index | 1.504 |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H315 — Causes skin irritation
- H318 — Causes serious eye damage
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Zhao Y, et al. Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective. Oxid Med Cell Longev. 2016;2016:2124638. [2]. Wu W, et al. Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway. Behav Brain Res. 2013 Sep 15;253:212-6. [3]. Kao TK, et al. Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. Exp Neurol. 2013 Sep;247:188-201. |
|---|
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Tetramethylpyrazine?
The CAS number of Tetramethylpyrazine is 1124-11-4.
What are the molecular formula and molecular weight of Tetramethylpyrazine?
Tetramethylpyrazine has molecular formula C8H12N2 and molecular weight 136.19 g/mol.
Is Tetramethylpyrazine hazardous?
Tetramethylpyrazine has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H318 — Causes serious eye damage.
What are the upstream and downstream products of Tetramethylpyrazine?
For Tetramethylpyrazine, Upstream Products: Acetoin, 2,5-dichloro-3,6-dimethylpyrazine, Trimethylaluminium; Downstream Products: 3,5,6-Trimethylpyrazine-2-carboxylic acid, (3,5,6-Trimethylpyrazin-2-yl)methanol, 3,5,6-trimethylpyrazine-2-carbaldehyde.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Tetramethylpyrazine (CAS 1124-11-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-38669-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.