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3',4'-Difluoroacetophenone

Also known as: 1-(3,4-Difluorophenyl)ethan-1-one, 1-(3,4-Difluorophenyl)ethanone, 1-(3,4-Difluorophenyl)-1-ethanone, 3,4-Difluoroacetophenone, 4-Acetyl-1,2-difluorobenzene, Ethanone, 1-(3,4-difluorophenyl)-, EINECS 206-717-7, MFCD00009891, OTAVA-BB BB7020410077

3',4'-Difluoroacetophenone (CAS 369-33-5) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C8H6F2O and a molecular weight of 156.129 g/mol. Key properties include a melting point of 19-20 °C(lit.), a boiling point of 206.5±20.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 75.0±0.0 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
369-33-5
Jingsj CID
J-38597-7
Molecular Formula
C8H6F2O
Molecular Weight
156.129 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point19-20 °C(lit.)
Boiling Point206.5±20.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point75.0±0.0 °C
Exact Mass156.038666
PSA17.07000
LogP1.73
Vapor Pressure0.2±0.4 mmHg at 25°C
Refractive Index1.473
Additional PropertyINSOLUBLE

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2914700090
SummaryHS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 3',4'-Difluoroacetophenone?

The CAS number of 3',4'-Difluoroacetophenone is 369-33-5.

What are the molecular formula and molecular weight of 3',4'-Difluoroacetophenone?

3',4'-Difluoroacetophenone has molecular formula C8H6F2O and molecular weight 156.129 g/mol.

Is 3',4'-Difluoroacetophenone hazardous?

3',4'-Difluoroacetophenone has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 3',4'-Difluoroacetophenone?

For 3',4'-Difluoroacetophenone, Upstream Products: 1,2-Difluorobenzene, Acetyl chloride, 3,4-Difluorobenzoyl chloride; Downstream Products: 3,4-Difluorobenzoic acid, 3-Fluorobenzoic acid, (S)-1-(3,4-difluorophenyl)ethanamine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "3',4'-Difluoroacetophenone (CAS 369-33-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-38597-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.