5-Fluorouridine

Also known as: 5-FUrd, 5-FU, 5-fluoro-1-β-D-ribofuranosyluracil, FURD, 1-(β-D-ribofuranosyl)-5-fluorouracil, 5-fluoro-uridine, fluorouridine

5-Fluorouridine (CAS 316-46-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C9H11FN2O6 and a molecular weight of 262.192 g/mol. Key properties include a melting point of 182-184 °C and a density of 1.8±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 316-46-1
Jingsj CID: J-38076-7
Molecular Formula: C₉H₁₁FN₂O₆
Molecular Weight: 262.192 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	182-184 °C
Density	1.8±0.1 g/cm3
Exact Mass	262.060120
PSA	124.78000
LogP	-1.34
Refractive Index	1.641
Additional Property	soluble

Activity & Biological Data

Additional Information	[1]. Wu FL , et al. Gelatinases-stimuli nanoparticles encapsulating 5-fluorouridine and 5-aza-2'-deoxycytidine enhance the sensitivity of gastric cancer cells to chemical therapeutics. Cancer Lett. 2015 Jul 10;363(1):7-16. [2]. Hu N, et al. Strengthening Gastric Cancer Therapy by Trastuzumab-Conjugated Nanoparticles with Simultaneous Encapsulation of Anti-MiR-21 and 5-Fluorouridine. Cell Physiol Biochem. 2017;44(6):2158-2173. [3]. Glazer RI, et al. Association of cell lethality with incorporation of 5-fluorouracil and 5-fluorouridine into nuclear RNA in human colon carcinoma cells in culture. Mol Pharmacol. 1982 Mar;21(2):468-73. [4]. Kanzawa F, et al. Differences between 5-fluoro-2'-deoxyuridine and 5-fluorouridine in their cytotoxic effect on growth of murine lymphoma L5178Y cells in in vivo and in vitro systems. Eur J Cancer. 1980 Aug;16(8):1087-92.

Additional Information

[1]. Wu FL , et al. Gelatinases-stimuli nanoparticles encapsulating 5-fluorouridine and 5-aza-2'-deoxycytidine enhance the sensitivity of gastric cancer cells to chemical therapeutics. Cancer Lett. 2015 Jul 10;363(1):7-16. [2]. Hu N, et al. Strengthening Gastric Cancer Therapy by Trastuzumab-Conjugated Nanoparticles with Simultaneous Encapsulation of Anti-MiR-21 and 5-Fluorouridine. Cell Physiol Biochem. 2017;44(6):2158-2173. [3]. Glazer RI, et al. Association of cell lethality with incorporation of 5-fluorouracil and 5-fluorouridine into nuclear RNA in human colon carcinoma cells in culture. Mol Pharmacol. 1982 Mar;21(2):468-73. [4]. Kanzawa F, et al. Differences between 5-fluoro-2'-deoxyuridine and 5-fluorouridine in their cytotoxic effect on growth of murine lymphoma L5178Y cells in in vivo and in vitro systems. Eur J Cancer. 1980 Aug;16(8):1087-92.

Customs & Trade Information

HS Code	2942000000

Frequently Asked Questions

What is the CAS number of 5-Fluorouridine?

The CAS number of 5-Fluorouridine is 316-46-1.

What are the molecular formula and molecular weight of 5-Fluorouridine?

5-Fluorouridine has molecular formula C9H11FN2O6 and molecular weight 262.192 g/mol.

What are the upstream and downstream products of 5-Fluorouridine?

For 5-Fluorouridine, Upstream Products: Uridine, Cytidine, 5-Fluorouracil; Downstream Products: 5-Fluorouracil, 5-Fluorocytidine, choline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "5-Fluorouridine (CAS 316-46-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-38076-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.