Temozolomide

Also known as: 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide, 8-Carbamoyl-3-methylimidazo[5,1-d][1,2,3,5]tetrazin-4(3H)-one, Methazolastone, Temodal, Temodar, M&B 39831, NSC 362856, TZM

Temozolomide (CAS 85622-93-1) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C6H6N6O2 and a molecular weight of 194.151 g/mol. Key properties include a melting point of 212°C dec., a boiling point of 526.6±42.0 °C at 760 mmHg, a density of 2.0±0.1 g/cm3 and a flash point of 272.3±27.9 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 85622-93-1
Jingsj CID: J-38021-2
Molecular Formula: C₆H₆N₆O₂
Molecular Weight: 194.151 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	212°C dec.
Boiling Point	526.6±42.0 °C at 760 mmHg
Density	2.0±0.1 g/cm3
Flash Point	272.3±27.9 °C
Exact Mass	194.055222
PSA	108.17000
LogP	-1.32
Vapor Pressure	0.0±1.4 mmHg at 25°C
Refractive Index	1.895
Storage Conditions	2-8°C

GHS Safety & Compliance

Irritant / Health HazardSignal word: Danger

H302 — Harmful if swallowed
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation
H350 — May cause cancer
H360 — May damage fertility or the unborn child

Activity & Biological Data

Target	DNA alkylator[1]
Additional Information	[1]. Tentori L, et al. Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site. Blood. 2002 Mar 15;99(6):2241-4. [2]. Perazzoli G, et al. Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression. PLoS One. 2015 Oct 8;10(10):e0140131.

Target

DNA alkylator[1]

Additional Information

[1]. Tentori L, et al. Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site. Blood. 2002 Mar 15;99(6):2241-4. [2]. Perazzoli G, et al. Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression. PLoS One. 2015 Oct 8;10(10):e0140131.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Temozolomide?

The CAS number of Temozolomide is 85622-93-1.

What are the molecular formula and molecular weight of Temozolomide?

Temozolomide has molecular formula C6H6N6O2 and molecular weight 194.151 g/mol.

Is Temozolomide hazardous?

Temozolomide has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Temozolomide?

For Temozolomide, Upstream Products: iodomethane, 4-Amino-5-imidazolecarboxamide hydrochloride, 4-Nitrophenyl chloroformate; Downstream Products: Temozolomide acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Temozolomide (CAS 85622-93-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-38021-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.