Loperamide hydrochloride

Also known as: 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide hydrochloride, 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-, hydrochloride (1:1), Imodium, Imosec, Lopemid, Lopemin, Loperyl, Suprasec, Tebloc, Arret, Blox, Dissenten, Fortasec, R-18553 hydrochloride, EINECS 252-082-4, MFCD00058581

Loperamide hydrochloride (CAS 34552-83-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C29H34Cl2N2O2 and a molecular weight of 513.498 g/mol. Key properties include a melting point of 223-225°C, a boiling point of 647.2ºC at 760 mmHg and a flash point of 345.2ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 34552-83-5
Jingsj CID: J-37926-0
Molecular Formula: C₂₉H₃₄Cl₂N₂O₂
Molecular Weight: 513.498 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	223-225°C
Boiling Point	647.2ºC at 760 mmHg
Flash Point	345.2ºC
Exact Mass	512.199707
PSA	43.78000
LogP	5.82790

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed

Activity & Biological Data

Additional Information	[1]. Hanauer, S.B., The role of loperamide in gastrointestinal disorders. Rev Gastroenterol Disord, 2008. 8(1): p. 15-20. [2]. Litovitz, T., et al., Surveillance of loperamide ingestions: an analysis of 216 poison center reports. J Toxicol Clin Toxicol, 1997. 35(1): p. 11-9. [3]. http://www.drugs.com/mmx/loperamide-hydrochloride.html

Frequently Asked Questions

What is the CAS number of Loperamide hydrochloride?

The CAS number of Loperamide hydrochloride is 34552-83-5.

What are the molecular formula and molecular weight of Loperamide hydrochloride?

Loperamide hydrochloride has molecular formula C29H34Cl2N2O2 and molecular weight 513.498 g/mol.

Is Loperamide hydrochloride hazardous?

Loperamide hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.

What are the upstream and downstream products of Loperamide hydrochloride?

For Loperamide hydrochloride, Upstream Products: 4-(4-Chlorophenyl)piperidin-4-ol, 3,3-Diphenyltetrahydrofuran-2-ylidene(dimethyl)ammonium bromide, 4-Methyl-2-pentanone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Loperamide hydrochloride (CAS 34552-83-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37926-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.