Tenidap

Also known as: CP-66248, (3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide, (3Z)-5-chloro-3-[hydroxy(thiophen-2-yl)methylidene]-2-oxoindole-1-carboxamide, (Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide, 5-Chloro-2,3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide, AKOS 91367, Tenidapum

Tenidap (CAS 120210-48-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C14H9ClN2O3S and a molecular weight of 320.75 g/mol. Key properties include a melting point of 230° (dec), a boiling point of 523.9ºC at 760mmHg, a density of 1.58g/cm3 and a flash point of 270.7ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 120210-48-2
Jingsj CID: J-37353-5
Molecular Formula: C₁₄H₉ClN₂O₃S
Molecular Weight: 320.75 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	230° (dec)
Boiling Point	523.9ºC at 760mmHg
Density	1.58g/cm3
Flash Point	270.7ºC
Exact Mass	320.00200
PSA	111.87000
LogP	4.01840
Appearance	faint yellow to dark yellow
Vapor Pressure	7.42E-13mmHg at 25°C
Refractive Index	1.756
Storage Conditions	Store at +4°C
Additional Property	DMSO: soluble1mg/mL, clear (warmed)

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Target	COX-1:0.03 μM (IC50) COX-2:1.2 μM (IC50)
Additional Information	[1]. Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101. [2]. Blackburn WD Jr, et al. Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone. Arthritis Rheum. 1995 Oct;38(10):1447-56.

Target

COX-1:0.03 μM (IC50) COX-2:1.2 μM (IC50)

Additional Information

[1]. Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101. [2]. Blackburn WD Jr, et al. Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone. Arthritis Rheum. 1995 Oct;38(10):1447-56.

Frequently Asked Questions

What is the CAS number of Tenidap?

The CAS number of Tenidap is 120210-48-2.

What are the molecular formula and molecular weight of Tenidap?

Tenidap has molecular formula C14H9ClN2O3S and molecular weight 320.75 g/mol.

Is Tenidap hazardous?

Tenidap has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Tenidap?

For Tenidap, Upstream Products: 2-Thiophenecarbonyl chloride, 5-Chlorooxindole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tenidap (CAS 120210-48-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37353-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.