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3-Hydroxybutyric acid

Also known as: 3-Hydroxybutanoic acid, β-Hydroxybutyric acid, DL-3-Hydroxybutyric acid, DL-β-Hydroxybutyric acid, β-Hydroxy-n-butyric acid, 3-Hydroxybutanoate, beta-Hydroxybutyrate

3-Hydroxybutyric acid (CAS 300-85-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C4H8O3 and a molecular weight of 104.104 g/mol. Key properties include a melting point of 174-175℃, a boiling point of 269.2±0.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 121.0±19.1 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
300-85-6
Jingsj CID
J-37179-9
Molecular Formula
C4H8O3
Molecular Weight
104.104 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point174-175℃
Boiling Point269.2±0.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point121.0±19.1 °C
Exact Mass104.047340
PSA57.53000
LogP-1.14
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.455

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetHuman Endogenous Metabolite
Additional Information[1]. Hsu TT, et al. 3-Hydroxybutyric acid interacts with lipid monolayers at concentrations that impair consciousness. Langmuir. 2013 Feb 12;29(6):1948-55.

Frequently Asked Questions

What is the CAS number of 3-Hydroxybutyric acid?

The CAS number of 3-Hydroxybutyric acid is 300-85-6.

What are the molecular formula and molecular weight of 3-Hydroxybutyric acid?

3-Hydroxybutyric acid has molecular formula C4H8O3 and molecular weight 104.104 g/mol.

Is 3-Hydroxybutyric acid hazardous?

3-Hydroxybutyric acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 3-Hydroxybutyric acid?

For 3-Hydroxybutyric acid, Upstream Products: Butyric acid, 1,2-dichloroethane, Ethyl 3-hydroxybutyrate; Downstream Products: Methyl (R)-(-)-3-hydroxybutyrate, Methyl (S)-(+)-3-hydroxybutyrate, (E)-2-Butenoic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "3-Hydroxybutyric acid (CAS 300-85-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37179-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.