Piperine
Also known as: 1-Piperoylpiperidine, (E,E)-1-Piperoylpiperidine, Bioperine, Piperin, 1-Piperonylpiperidine, 1-Piperylpiperidine, FEMA 2909, UNII:U71XL721QK, (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one, 1-(5-(3,4-Methylenedioxyphenyl)-1-oxo-2,4-pentadienyl)piperidine
Piperine (CAS 94-62-2) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C17H19NO3 and a molecular weight of 285.338 g/mol. Key properties include a melting point of 131-135 °C(lit.), a boiling point of 498.5±40.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 255.3±27.3 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 94-62-2
- Jingsj CID
- J-37143-8
- Molecular Formula
- C17H19NO3
- Molecular Weight
- 285.338 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 131-135 °C(lit.) |
|---|---|
| Boiling Point | 498.5±40.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 255.3±27.3 °C |
| Exact Mass | 285.136505 |
| PSA | 38.77000 |
| LogP | 2.66 |
| Vapor Pressure | 0.0±1.3 mmHg at 25°C |
| Refractive Index | 1.615 |
| Additional Property | 40 mg/L (18 ºC) |
GHS Safety & Compliance
- H302 — Harmful if swallowed
Activity & Biological Data
| Target | IC50: 61.94±0.054 μg/mL (P-glycoprotein, HeLa cell)[1] |
|---|---|
| Additional Information | [1]. Paarakh PM, et al. In vitro cytotoxic and in silico activity of piperine isolated from Piper nigrum fruits Linn. In Silico Pharmacol. 2015 Dec;3(1):9. Epub 2015 Oct 29. [2]. Meghwal M,et al. Piper nigrum and piperine: an update. Phytother Res. 2013 Aug;27(8):1121-30. [3]. Li C, et al. Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats. J Pharm Biomed Anal. 2016 Sep 5;128:286-93. [4]. Zhai WJ, et al. Piperine Plays an Anti-Inflammatory Role in Staphylococcus aureus Endometritis by Inhibiting Activation of NF-κB and MAPK Pathways in Mice. Evid Based Complement Alternat Med. 2016;2016:8597208. |
Customs & Trade Information
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Piperine?
The CAS number of Piperine is 94-62-2.
What are the molecular formula and molecular weight of Piperine?
Piperine has molecular formula C17H19NO3 and molecular weight 285.338 g/mol.
Is Piperine hazardous?
Piperine has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.
What are the upstream and downstream products of Piperine?
For Piperine, Upstream Products: Piperic acid, 1-(piperidin-1-yl)prop-2-en-1-one, 3,4-(Methylenedioxy)cinnamic acid; Downstream Products: Tetraethyl ethylenetetracarboxylate, 1-Nitrosopiperidine, Piperic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Piperine (CAS 94-62-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-37143-8 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.