6,7-Dimethoxy-2-phenylquinoxaline

Also known as: Tyrphostin AG1296, AG-1296, AG 1296, 6,7-Dimethoxy-3-phenylquinoxaline, Quinoxaline, 6,7-dimethoxy-2-phenyl-, 2-phenyl-6,7-dimethoxyquinoxaline

6,7-Dimethoxy-2-phenylquinoxaline (CAS 146535-11-7) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C16H14N2O2 and a molecular weight of 266.295 g/mol. Key properties include a boiling point of 420.2±40.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 151.8±17.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 146535-11-7
Jingsj CID: J-3661-3
Molecular Formula: C₁₆H₁₄N₂O₂
Molecular Weight: 266.295 g/mol
Category: Aromatic Hydrocarbons
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Boiling Point	420.2±40.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	151.8±17.6 °C
Exact Mass	266.105530
PSA	44.24000
LogP	3.76
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.618

Activity & Biological Data

Target	PDGFRα PDGFRβ
Additional Information	[1]. Gazit A, etm, al. Tyrphostins. 5. Potent inhibitors of platelet-derived growth factor receptor tyrosine kinase: structure-activity relationships in quinoxalines, quinolines, and indole tyrphostins. Comparative Study J Med Chem. 1996 May 24; 39(11): 2170-7. [2]. Kovalenko M, et, al. Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation. Cancer Res. 1994 Dec 1; 54(23): 6106-14. [3]. Tse KF, et, al. Inhibition of the transforming activity of FLT3 internal tandem duplication mutants from AML patients by a tyrosine kinase inhibitor. Leukemia. 2002 Oct; 16(10): 2027-36. [4]. Li Y, et, al. Tyrphostin AG1296, a platelet-derived growth factor receptor inhibitor, induces apoptosis, and reduces viability and migration of PLX4032-resistant melanoma cells. Onco Targets Ther. 2015 May 14; 8: 1043-51. [5]. Dong M, et, al. AG1296 enhances plaque stability via inhibiting inflammatory responses and decreasing MMP-2 and MMP-9 expression in ApoE-/- mice. Biochem Biophys Res Commun. 2017 Aug 5;489(4):426-431.

Target

PDGFRα PDGFRβ

Additional Information

[1]. Gazit A, etm, al. Tyrphostins. 5. Potent inhibitors of platelet-derived growth factor receptor tyrosine kinase: structure-activity relationships in quinoxalines, quinolines, and indole tyrphostins. Comparative Study J Med Chem. 1996 May 24; 39(11): 2170-7. [2]. Kovalenko M, et, al. Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation. Cancer Res. 1994 Dec 1; 54(23): 6106-14. [3]. Tse KF, et, al. Inhibition of the transforming activity of FLT3 internal tandem duplication mutants from AML patients by a tyrosine kinase inhibitor. Leukemia. 2002 Oct; 16(10): 2027-36. [4]. Li Y, et, al. Tyrphostin AG1296, a platelet-derived growth factor receptor inhibitor, induces apoptosis, and reduces viability and migration of PLX4032-resistant melanoma cells. Onco Targets Ther. 2015 May 14; 8: 1043-51. [5]. Dong M, et, al. AG1296 enhances plaque stability via inhibiting inflammatory responses and decreasing MMP-2 and MMP-9 expression in ApoE-/- mice. Biochem Biophys Res Commun. 2017 Aug 5;489(4):426-431.

Frequently Asked Questions

What is the CAS number of 6,7-Dimethoxy-2-phenylquinoxaline?

The CAS number of 6,7-Dimethoxy-2-phenylquinoxaline is 146535-11-7.

What are the molecular formula and molecular weight of 6,7-Dimethoxy-2-phenylquinoxaline?

6,7-Dimethoxy-2-phenylquinoxaline has molecular formula C16H14N2O2 and molecular weight 266.295 g/mol.

What are the upstream and downstream products of 6,7-Dimethoxy-2-phenylquinoxaline?

For 6,7-Dimethoxy-2-phenylquinoxaline, Upstream Products: 1,2-Dimethoxy-4,5-dinitrobenzene, Phenylglyoxal monohydrate, 1,2-Diamino-4,5-dimethoxybenzene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "6,7-Dimethoxy-2-phenylquinoxaline (CAS 146535-11-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-3661-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.