5'-N-Ethylcarboxamidoadenosine

Also known as: NECA, Adenosine 5'-N-ethylcarboxamide, 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide, 5'-Ethylcarboxamido adenosine, 5'-N-Ethylcarboxamidoadenosine hemihydrate

5'-N-Ethylcarboxamidoadenosine (CAS 35920-39-9) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C12H16N6O4 and a molecular weight of 308.293 g/mol. Key properties include a melting point of 229-231ºC and a density of 1.9±0.1 g/cm3. It is classified under GHS with signal word Danger and hazard statements H300. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 35920-39-9
Jingsj CID: J-36604-1
Molecular Formula: C₁₂H₁₆N₆O₄
Molecular Weight: 308.293 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	229-231ºC
Density	1.9±0.1 g/cm3
Exact Mass	308.123291
PSA	148.41000
LogP	-0.48
Refractive Index	1.829
Additional Property	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.2 mg/mL Solutions may be stored for several days at 4?#x00b0;C.

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H300

Activity & Biological Data

Target	Adenosine receptor[1]
Additional Information	[1]. Knapp CM, et al. Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self-administration. Pharmacol Biochem Behav. 2001 Apr;68(4):797-803. [2]. Elsherbiny NM, et al. Reno-protective effect of NECA in diabetic nephropathy: implication of IL-18 and ICAM-1. Eur Cytokine Netw. 2012 Jul-Sep;23(3):78-86.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 5'-N-Ethylcarboxamidoadenosine?

The CAS number of 5'-N-Ethylcarboxamidoadenosine is 35920-39-9.

What are the molecular formula and molecular weight of 5'-N-Ethylcarboxamidoadenosine?

5'-N-Ethylcarboxamidoadenosine has molecular formula C12H16N6O4 and molecular weight 308.293 g/mol.

Is 5'-N-Ethylcarboxamidoadenosine hazardous?

5'-N-Ethylcarboxamidoadenosine has GHS signal word Danger and hazard statements H300.

What are the upstream and downstream products of 5'-N-Ethylcarboxamidoadenosine?

For 5'-N-Ethylcarboxamidoadenosine, Upstream Products: Ethylamine, 2',3'-O-Isopropylideneadenosine, Adenosine-5'-carboxylic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "5'-N-Ethylcarboxamidoadenosine (CAS 35920-39-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-36604-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.