Sertindole

Also known as: 1-[2-[4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinone, 2-Imidazolidinone, 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl]ethyl]-, LU 23-174, Serdolect, Sellect, Zerdol, 1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one, 1-(4-Fluorophenyl)-5-chloro-3-[1-[2-[(tetrahydro-2-oxo-1H-imidazol)-1-yl]ethyl]piperidin-4-yl]-1H-indole

Sertindole (CAS 106516-24-9) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C24H26ClFN4O and a molecular weight of 440.941 g/mol. Key properties include a melting point of 95-100ºC, a boiling point of 592.1±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 311.9±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 106516-24-9
Jingsj CID: J-36290-0
Molecular Formula: C₂₄H₂₆ClFN₄O
Molecular Weight: 440.941 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	95-100ºC
Boiling Point	592.1±50.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	311.9±30.1 °C
Exact Mass	440.177917
PSA	40.51000
LogP	5.26
Appearance	off-white
Vapor Pressure	0.0±1.7 mmHg at 25°C
Refractive Index	1.671
Storage Conditions	2-8°C
Additional Property	DMSO: >10mg/mL

GHS Safety & Compliance

IrritantSignal word: Warning

H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation
H413

Activity & Biological Data

Additional Information	[1]. Juruena, M.F., E.P. de Sena, and I.R. de Oliveira, Sertindole in the management of schizophrenia. J Cent Nerv Syst Dis, 2011. 3: p. 75-85. [2]. Kane, J.M. and C.A. Tamminga, Sertindole (Serdolect): preclinical and clinical findings of a new atypical antipsychotic. Expert Opin Investig Drugs, 1997. 6(11): p. 1729-41. [3]. Murdoch, D. and G.M. Keating, Sertindole : a review of its use in schizophrenia. CNS Drugs, 2006. 20(3): p. 233-55.

Additional Information

[1]. Juruena, M.F., E.P. de Sena, and I.R. de Oliveira, Sertindole in the management of schizophrenia. J Cent Nerv Syst Dis, 2011. 3: p. 75-85. [2]. Kane, J.M. and C.A. Tamminga, Sertindole (Serdolect): preclinical and clinical findings of a new atypical antipsychotic. Expert Opin Investig Drugs, 1997. 6(11): p. 1729-41. [3]. Murdoch, D. and G.M. Keating, Sertindole : a review of its use in schizophrenia. CNS Drugs, 2006. 20(3): p. 233-55.

Frequently Asked Questions

What is the CAS number of Sertindole?

The CAS number of Sertindole is 106516-24-9.

What are the molecular formula and molecular weight of Sertindole?

Sertindole has molecular formula C24H26ClFN4O and molecular weight 440.941 g/mol.

Is Sertindole hazardous?

Sertindole has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Sertindole?

For Sertindole, Upstream Products: 1-(2-chloroethyl)imidazolidin-2-one, 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole, 5-Chloro-1-(4-fluorophenyl)-1H-indole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Sertindole (CAS 106516-24-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-36290-0 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.