Phenacetin

Also known as: Acetophenetidine, p-Ethoxyacetanilide, N-(4-Ethoxyphenyl)acetamide, 4'-Ethoxyacetanilide, Aceto-p-phenetidin, N-Acetyl-4-ethoxyaniline, Fenacetina, Phenacetine

Phenacetin (CAS 62-44-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C10H13NO2 and a molecular weight of 179.216 g/mol. Key properties include a melting point of 133-136 °C(lit.), a boiling point of 323.6±44.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 149.5±28.4 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed and H350 — May cause cancer. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 62-44-2
Jingsj CID: J-35918-2
Molecular Formula: C₁₀H₁₃NO₂
Molecular Weight: 179.216 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	133-136 °C(lit.)
Boiling Point	323.6±44.0 °C at 760 mmHg
Density	1.0±0.1 g/cm3
Flash Point	149.5±28.4 °C
Exact Mass	179.094635
PSA	38.33000
LogP	2.01
Vapor Pressure	0.0±0.7 mmHg at 25°C
Refractive Index	1.506
Stability	Stable. Incompatible with strong oxidizing agents, strong acids.
Additional Property	0.076 g/100 mL

GHS Safety & Compliance

Irritant / Health HazardSignal word: Danger

H302 — Harmful if swallowed
H350 — May cause cancer

Activity & Biological Data

Target	COX-3:102 μM (IC50)
Additional Information	[1]. Chandrasekharan NV, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13926-31. [2]. Brix, A.E., Renal papillary necrosis. Toxicol Pathol, 2002. 30(6): p. 672-4. [3]. Dubach, U.C., B. Rosner, and T. Sturmer, An epidemiologic study of abuse of analgesic drugs. Effects of phenacetin and salicylate on mortality and cardiovascular morbidity (1968 to 1987). N Engl J Med, 1991. 324(3): p. 155-60.

Target

COX-3:102 μM (IC50)

Additional Information

[1]. Chandrasekharan NV, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13926-31. [2]. Brix, A.E., Renal papillary necrosis. Toxicol Pathol, 2002. 30(6): p. 672-4. [3]. Dubach, U.C., B. Rosner, and T. Sturmer, An epidemiologic study of abuse of analgesic drugs. Effects of phenacetin and salicylate on mortality and cardiovascular morbidity (1968 to 1987). N Engl J Med, 1991. 324(3): p. 155-60.

Customs & Trade Information

HS Code	2924291000

Frequently Asked Questions

What is the CAS number of Phenacetin?

The CAS number of Phenacetin is 62-44-2.

What are the molecular formula and molecular weight of Phenacetin?

Phenacetin has molecular formula C10H13NO2 and molecular weight 179.216 g/mol.

Is Phenacetin hazardous?

Phenacetin has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H350 — May cause cancer.

What are the upstream and downstream products of Phenacetin?

For Phenacetin, Upstream Products: p-Phenetidine, 1-Ethoxy-4-nitrobenzene, 4'-Ethoxyacetophenone; Downstream Products: 1-Bromo-2-ethoxybenzene, 6-Hydroxyquinoline, 1-(5-Amino-2-hydroxyphenyl)ethanone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Phenacetin (CAS 62-44-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35918-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.