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Diphenhydramine

Also known as: 2-benzhydryloxy-N,N-dimethylethanamine, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, n,n-dimethyl-4,4-diphenyl-3-oxabutylamine, Benzhydramine, DPH, Diphenhydramine Base

Diphenhydramine (CAS 58-73-1) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C17H21NO and a molecular weight of 255.36100 g/mol. Key properties include a melting point of 167-172°C, a boiling point of 343.7±27.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 101.5±26.0 °C. No supplier offers are currently listed; request a quote. Record last updated Nov 4, 2026.

CAS No.
58-73-1
Jingsj CID
J-35623-9
Molecular Formula
C17H21NO
Molecular Weight
255.36100 g/mol
Category
Aromatic Hydrocarbons
Last updated
11/4/2026

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Physicochemical Properties

Melting Point167-172°C
Boiling Point343.7±27.0 °C at 760 mmHg
Density1.0±0.1 g/cm3
Flash Point101.5±26.0 °C
Exact Mass255.162308
PSA12.47000
LogP3.66
Vapor Pressure0.0±0.8 mmHg at 25°C
Refractive Index1.551

Activity & Biological Data

Additional Information[1]. Jason P Berninger, et al. Effects of the antihistamine diphenhydramine on selected aquatic organisms. Environ Toxicol Chem. 2011 Sep;30(9):2065-72.

Customs & Trade Information

HS Code2922199090
Summary2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Diphenhydramine?

The CAS number of Diphenhydramine is 58-73-1.

What are the molecular formula and molecular weight of Diphenhydramine?

Diphenhydramine has molecular formula C17H21NO and molecular weight 255.36100 g/mol.

What are the upstream and downstream products of Diphenhydramine?

For Diphenhydramine, Upstream Products: N,N-Dimethylethanolamine, Chlorodiphenylmethane, Dimethylamine; Downstream Products: 2-(Diphenylmethoxy)-N-methylethylamine, Benzhydrol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Diphenhydramine (CAS 58-73-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35623-9 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.