Amphotericin B
Also known as: Fungizone, Abelcet, AmBisome, Amphocin, Amphozone, Fungilin, Halizon, LNS-AmB, NSC 527017, Ampho-moronal, Apothecon, Kalsome 10, NS 718, Abelecet, Fungizona, Amphotec, Soluble amphotericin B
Amphotericin B (CAS 1397-89-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C47H73NO17 and a molecular weight of 924.079 g/mol. Key properties include a melting point of >170°C, a boiling point of 1140.4±65.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 643.5±34.3 °C. It is classified under GHS with signal word Warning and hazard statements H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.
- CAS No.
- 1397-89-3
- Jingsj CID
- J-35545-3
- Molecular Formula
- C47H73NO17
- Molecular Weight
- 924.079 g/mol
- Category
- Organic Compounds
- Last updated
- 11/3/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | >170°C |
|---|---|
| Boiling Point | 1140.4±65.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 643.5±34.3 °C |
| Exact Mass | 923.487854 |
| PSA | 319.61000 |
| LogP | 1.16 |
| Vapor Pressure | 0.0±0.6 mmHg at 25°C |
| Refractive Index | 1.614 |
| Additional Property | sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20?#x00b0;C. Stable at 37?#x00b0;C for 3 days. | <0.1 g/100 mL at 21 ºC |
GHS Safety & Compliance
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Fungal[1] |
|---|---|
| Additional Information | [1]. Sau K, et al. The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism. J Biol Chem. 2003 Sep 26;278(39):37561-8. Epub 2003 Jul 14. [2]. Barwicz J, et al. The effect of aggregation state of amphotericin-B on its interactions with cholesterol- or ergosterol-containing phosphatidylcholine monolayers. Chem Phys Lipids. 1997 Feb 28;85(2):145-55. [3]. Ramos H, et al. Amphotericin B kills unicellular leishmanias by forming aqueous pores permeable to small cations and anions. J Membr Biol. 1996 Jul;152(1):65-75. [4]. Demaimay R, et al. Pharmacological studies of a new derivative of amphotericin B, MS-8209, in mouse and hamster scrapie. J Gen Virol. 1994 Sep;75 (Pt 9):2499-503. [5]. Adams ML, et al. Amphotericin B encapsulated in micelles based on poly(ethylene oxide)-block-poly(L-amino acid) derivatives exerts reduced in vitro hemolysis but maintains potent in vivo antifungal activity. Biomacromolecules. 2003 May-Jun;4(3):750-7. |
Frequently Asked Questions
What is the CAS number of Amphotericin B?
The CAS number of Amphotericin B is 1397-89-3.
What are the molecular formula and molecular weight of Amphotericin B?
Amphotericin B has molecular formula C47H73NO17 and molecular weight 924.079 g/mol.
Is Amphotericin B hazardous?
Amphotericin B has GHS signal word Warning and hazard statements H335 — May cause respiratory irritation.
What are the upstream and downstream products of Amphotericin B?
For Amphotericin B, Upstream Products: Amphotericin B methyl ester.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Amphotericin B (CAS 1397-89-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35545-3 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.