Zanamivir

Also known as: 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid, 4-Guanidino-Neu5Ac2en, 5-(acetylamino)-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid, GG 167, Relenza, Zanamivir Hydrate, UNII-L6O3XI777I, GANA

Zanamivir (CAS 139110-80-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C12H20N4O7 and a molecular weight of 332.310 g/mol. Key properties include a melting point of 256ºC (dec.) and a density of 1.8±0.1 g/cm3. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 139110-80-8
Jingsj CID: J-35543-1
Molecular Formula: C₁₂H₂₀N₄O₇
Molecular Weight: 332.310 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	256ºC (dec.)
Density	1.8±0.1 g/cm3
Exact Mass	332.133209
PSA	198.22000
LogP	-4.13
Refractive Index	1.679
Storage Conditions	2~8℃

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Activity & Biological Data

Target	IC50: 0.95 nM (Influenza A); 2.7 nM (Influenza B)[1]
Additional Information	[1]. Gubareva LV, et al. Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates ofinfluenza virus and neuraminidase inhibitor-resistant variants. Antimicrob Agents Chemother. 2001 Dec;45(12):3403-8. [2]. McKimm-Breschkin JL, et al. Management of influenza virus infections with neuraminidase inhibitors: detection, incidence, and implications of drug resistance. Treat Respir Med. 2005;4(2):107-16. [3]. Shanmugam S, et al. Zanamivir oral delivery: enhanced plasma and lung bioavailability in rats. Biomol Ther (Seoul). 2013 Mar;21(2):161-9.

Target

IC50: 0.95 nM (Influenza A); 2.7 nM (Influenza B)[1]

Additional Information

[1]. Gubareva LV, et al. Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates ofinfluenza virus and neuraminidase inhibitor-resistant variants. Antimicrob Agents Chemother. 2001 Dec;45(12):3403-8. [2]. McKimm-Breschkin JL, et al. Management of influenza virus infections with neuraminidase inhibitors: detection, incidence, and implications of drug resistance. Treat Respir Med. 2005;4(2):107-16. [3]. Shanmugam S, et al. Zanamivir oral delivery: enhanced plasma and lung bioavailability in rats. Biomol Ther (Seoul). 2013 Mar;21(2):161-9.

Frequently Asked Questions

What is the CAS number of Zanamivir?

The CAS number of Zanamivir is 139110-80-8.

What are the molecular formula and molecular weight of Zanamivir?

Zanamivir has molecular formula C12H20N4O7 and molecular weight 332.310 g/mol.

Is Zanamivir hazardous?

Zanamivir has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Zanamivir?

For Zanamivir, Upstream Products: 1H-Pyrazole-1-carboximidamide hydrochloride, 5-(Acetylamino)-4-amino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid methyl ester 7,8,9-triacetate, Methyl 5-acetamido-7,8,9-O-triacetyl-2,6-anhydro-4-azido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Zanamivir (CAS 139110-80-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35543-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.