Ranitidine

Also known as: Zantac, AH-19065, Ranitidine base, 1,1-Ethenediamine, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-, N-[2-[[5-[(Dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-N'-methyl-2-nitroethene-1,1-diamine

Ranitidine (CAS 66357-35-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C13H22N4O3S and a molecular weight of 314.404 g/mol. Key properties include a melting point of 69-70°C, a boiling point of 437.1±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 218.2±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 66357-35-5
Jingsj CID: J-35519-1
Molecular Formula: C₁₃H₂₂N₄O₃S
Molecular Weight: 314.404 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	69-70°C
Boiling Point	437.1±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	218.2±28.7 °C
Exact Mass	314.141266
PSA	111.56000
LogP	1.23
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.559
Storage Conditions	Desiccate at +4°C
Additional Property	24.7 mg/mL

Activity & Biological Data

Target	H2 Receptor:3.3 μM (IC50) CYP2C19 CYP2C9
Additional Information	[1]. A W Herling, et al. Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460). Agents Actions. 1987 Feb;20(1-2):35-9. [2]. A Leucuta, et al. A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact. 2004;20(4):273-81. [3]. Antonio Francesco Ciccaglione, et al. Pylera® plus ranitidine vs Pylera® plus esomeprazole in first-line treatment of Helicobacter pylori infection: Two pilot studies. Helicobacter. 2019 Oct;24(5):e12606.

Target

H2 Receptor:3.3 μM (IC50) CYP2C19 CYP2C9

Additional Information

[1]. A W Herling, et al. Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460). Agents Actions. 1987 Feb;20(1-2):35-9. [2]. A Leucuta, et al. A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact. 2004;20(4):273-81. [3]. Antonio Francesco Ciccaglione, et al. Pylera® plus ranitidine vs Pylera® plus esomeprazole in first-line treatment of Helicobacter pylori infection: Two pilot studies. Helicobacter. 2019 Oct;24(5):e12606.

Customs & Trade Information

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Ranitidine?

The CAS number of Ranitidine is 66357-35-5.

What are the molecular formula and molecular weight of Ranitidine?

Ranitidine has molecular formula C13H22N4O3S and molecular weight 314.404 g/mol.

What are the upstream and downstream products of Ranitidine?

For Ranitidine, Upstream Products: 5-[[(2-Aminoethyl)thio]methyl]-N,N-dimethyl-2-furanmethanamine, Carbon, 1,1-Bis(methylthio)-2-nitroethylene; Downstream Products: Ranitidine hydrochloride, 5-[(Dimethylamino)methyl]-2-furanmethanol, 5,6-Dihydro-3-(methylamino)-2H-1,4-thiazin-2-one Oxime Hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ranitidine (CAS 66357-35-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35519-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.