Naftopidil

Also known as: KT-611, Avishot, Flivas, 1-[4-(2-Methoxyphenyl)piperazin-1-yl]-3-(1-naphthyloxy)propan-2-ol, 4-(2-Methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-1-piperazineethanol, (±)-1-(4-(2-Methoxyphenyl)piperazinyl)-3-(1-naphthyloxy)propan-2-ol, 1-[4-(2-Methoxyphenyl)-1-piperazinyl]-3-(1-naphthyloxy)-2-propanol

Naftopidil (CAS 57149-07-2) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C24H28N2O3 and a molecular weight of 392.491 g/mol. Key properties include a melting point of 127 °C, a boiling point of 602.8±55.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 318.3±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 57149-07-2
Jingsj CID: J-35322-5
Molecular Formula: C₂₄H₂₈N₂O₃
Molecular Weight: 392.491 g/mol
Category: Aromatic Hydrocarbons
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	127 °C
Boiling Point	602.8±55.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	318.3±31.5 °C
Exact Mass	392.209991
PSA	45.17000
LogP	4.81
Vapor Pressure	0.0±1.8 mmHg at 25°C
Refractive Index	1.619
Additional Property	methanol: >10 mg/mL

Activity & Biological Data

Additional Information	[1]. Sakai, H., et al., [Efficacy of naftopidil in patients with overactive bladder associated with benign prostatic hyperplasia: prospective randomized controlled study to compare differences in efficacy between morning and evening medication]. Hinyokika Kiyo [2]. Takei, R., et al., Naftopidil, a novel alpha1-adrenoceptor antagonist, displays selective inhibition of canine prostatic pressure and high affinity binding to cloned human alpha1-adrenoceptors. Jpn J Pharmacol, 1999. 79(4): p. 447-54.

Additional Information

[1]. Sakai, H., et al., [Efficacy of naftopidil in patients with overactive bladder associated with benign prostatic hyperplasia: prospective randomized controlled study to compare differences in efficacy between morning and evening medication]. Hinyokika Kiyo [2]. Takei, R., et al., Naftopidil, a novel alpha1-adrenoceptor antagonist, displays selective inhibition of canine prostatic pressure and high affinity binding to cloned human alpha1-adrenoceptors. Jpn J Pharmacol, 1999. 79(4): p. 447-54.

Customs & Trade Information

HS Code	2942000000

Frequently Asked Questions

What is the CAS number of Naftopidil?

The CAS number of Naftopidil is 57149-07-2.

What are the molecular formula and molecular weight of Naftopidil?

Naftopidil has molecular formula C24H28N2O3 and molecular weight 392.491 g/mol.

What are the upstream and downstream products of Naftopidil?

For Naftopidil, Upstream Products: α-Naphthyl Glycidyl Ether, 1-(2-Methoxyphenyl)piperazine, 1-Naphthol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Naftopidil (CAS 57149-07-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35322-5 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.