Piroxicam

Also known as: Feldene, 4-Hydroxy-2-methyl-N-(2-pyridinyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, 4-Hydroxy-2-methyl-N-(pyridin-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, Piroxicam (USP), CHF 1251, Pyroxicam

Piroxicam (CAS 36322-90-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H13N3O4S and a molecular weight of 331.346 g/mol. Key properties include a melting point of 198-200°C, a boiling point of 568.5±60.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 297.6±32.9 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 36322-90-4
Jingsj CID: J-33651-6
Molecular Formula: C₁₅H₁₃N₃O₄S
Molecular Weight: 331.346 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	198-200°C
Boiling Point	568.5±60.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	297.6±32.9 °C
Exact Mass	331.062683
PSA	107.98000
LogP	2.23
Vapor Pressure	0.0±1.6 mmHg at 25°C
Refractive Index	1.692
Storage Conditions	2-8°C

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed

Activity & Biological Data

Target	COX-2:25 μM (IC50, in human monocytes) COX-1:47 μM (IC50, in human monocytes)
Additional Information	[1]. Kato M, et al. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes. J Pharm Pharmacol. 2001 Dec;53(12):1679-85. [2]. Mohammed SI, et al. Effects of the cyclooxygenase inhibitor, piroxicam, on tumor response, apoptosis, and angiogenesis in a canine model of human invasive urinary bladder cancer. Cancer Res. 2002 Jan 15;62(2):356-8. [3]. Silva J, et al. Synergistic Effect of Carboplatin and Piroxicam on Two Bladder Cancer Cell Lines. Anticancer Res. 2017 Apr;37(4):1737-1745.

Target

COX-2:25 μM (IC50, in human monocytes) COX-1:47 μM (IC50, in human monocytes)

Additional Information

[1]. Kato M, et al. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes. J Pharm Pharmacol. 2001 Dec;53(12):1679-85. [2]. Mohammed SI, et al. Effects of the cyclooxygenase inhibitor, piroxicam, on tumor response, apoptosis, and angiogenesis in a canine model of human invasive urinary bladder cancer. Cancer Res. 2002 Jan 15;62(2):356-8. [3]. Silva J, et al. Synergistic Effect of Carboplatin and Piroxicam on Two Bladder Cancer Cell Lines. Anticancer Res. 2017 Apr;37(4):1737-1745.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Piroxicam?

The CAS number of Piroxicam is 36322-90-4.

What are the molecular formula and molecular weight of Piroxicam?

Piroxicam has molecular formula C15H13N3O4S and molecular weight 331.346 g/mol.

Is Piroxicam hazardous?

Piroxicam has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.

What are the upstream and downstream products of Piroxicam?

For Piroxicam, Upstream Products: 2-Aminopyridine, N-Methylsaccharin, 2-Chloro-N-pyridin-2-ylacetamide; Downstream Products: Ampiroxicam, Droxicam, N-Methylsaccharin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Piroxicam (CAS 36322-90-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33651-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.