2,4,6-Trihydroxyacetophenone
Also known as: 2',4',6'-Trihydroxyacetophenone, Phloroacetophenone, Phloracetophenone, THAP, 2-Acetylphloroglucinol, 1-(2,4,6-Trihydroxyphenyl)ethanone, Ethanone, 1-(2,4,6-trihydroxyphenyl)-
2,4,6-Trihydroxyacetophenone (CAS 480-66-0) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C8H8O4 and a molecular weight of 168.147 g/mol. Key properties include a melting point of 219-221 °C(lit.), a boiling point of 333.2±22.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 169.5±18.8 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 480-66-0
- Jingsj CID
- J-33626-0
- Molecular Formula
- C8H8O4
- Molecular Weight
- 168.147 g/mol
- Category
- Ketones
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 219-221 °C(lit.) |
|---|---|
| Boiling Point | 333.2±22.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 169.5±18.8 °C |
| Exact Mass | 168.042252 |
| PSA | 77.76000 |
| LogP | 2.07 |
| Vapor Pressure | 0.0±0.8 mmHg at 25°C |
| Refractive Index | 1.641 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Cholesterol 7α-hydroxylase[1], Mrp2[2] |
|---|---|
| Additional Information | [1]. Charoenteeraboon J, et al. Induction of human cholesterol 7alpha-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone. Eur J Pharmacol. 2005 May 16;515(1-3):43-6. [2]. Piyachaturawat P, et al. Choleretic activity of phloracetophenone in rats: structure-function studies using acetophenone analogues. Eur J Pharmacol. 2000 Jan 10;387(2):221-7. |
Customs & Trade Information
| HS Code | 2914501900 |
|---|---|
| Summary | 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of 2,4,6-Trihydroxyacetophenone?
The CAS number of 2,4,6-Trihydroxyacetophenone is 480-66-0.
What are the molecular formula and molecular weight of 2,4,6-Trihydroxyacetophenone?
2,4,6-Trihydroxyacetophenone has molecular formula C8H8O4 and molecular weight 168.147 g/mol.
Is 2,4,6-Trihydroxyacetophenone hazardous?
2,4,6-Trihydroxyacetophenone has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of 2,4,6-Trihydroxyacetophenone?
For 2,4,6-Trihydroxyacetophenone, Upstream Products: Phloroglucinol, Acetyl chloride, Acetonitrile; Downstream Products: Flavokawain A, 5,7-Dihydroxychromone, Luteolin.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2,4,6-Trihydroxyacetophenone (CAS 480-66-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33626-0 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.