Itopride

Also known as: Ganaton, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxybenzamide, N-[4-[2-(Dimethylamino)ethoxy]benzyl]-3,4-dimethoxybenzamide, Benzamide, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy-, MFCD00867431, UNII-81BMQ80QRL

Itopride (CAS 122898-67-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H26N2O4 and a molecular weight of 358.431 g/mol. Key properties include a melting point of 185-187 °C(lit.), a boiling point of 510.1±50.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 262.3±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 122898-67-3
Jingsj CID: J-33478-1
Molecular Formula: C₂₀H₂₆N₂O₄
Molecular Weight: 358.431 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	185-187 °C(lit.)
Boiling Point	510.1±50.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	262.3±30.1 °C
Exact Mass	358.189270
PSA	60.03000
LogP	2.43
Vapor Pressure	0.0±1.3 mmHg at 25°C
Refractive Index	1.552
Additional Property	18 g/100 mL (20 ºC)

Activity & Biological Data

Target	D2 Receptor Acetylcholinesterase
Additional Information	[1]. Iwanaga Y, et al. A novel water-soluble dopamine-2 antagonist with anticholinesterase activity in gastrointestinal motor activity. Comparison with domperidone and neostigmine. Gastroenterology. 1990 Aug;99(2):401-8. [2]. Kim YS, et al. Effect of itopride, a new prokinetic, in patients with mild GERD: a pilot study. World J Gastroenterol. 2005 Jul 21;11(27):4210-4. [3]. Hyun Chul Lim, et al. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Yonsei Med J. 2008 Jun 30;49(3):472-8. [4]. Kenjiro Matsumoto, et al. Validation of 13 C-Acetic Acid Breath Test by Measuring Effects of Loperamide, Morphine, Mosapride, and Itopride on Gastric Emptying in Mice. Biol Pharm Bull. 2008 Oct;31(10):1917-22.

Target

D2 Receptor Acetylcholinesterase

Additional Information

[1]. Iwanaga Y, et al. A novel water-soluble dopamine-2 antagonist with anticholinesterase activity in gastrointestinal motor activity. Comparison with domperidone and neostigmine. Gastroenterology. 1990 Aug;99(2):401-8. [2]. Kim YS, et al. Effect of itopride, a new prokinetic, in patients with mild GERD: a pilot study. World J Gastroenterol. 2005 Jul 21;11(27):4210-4. [3]. Hyun Chul Lim, et al. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Yonsei Med J. 2008 Jun 30;49(3):472-8. [4]. Kenjiro Matsumoto, et al. Validation of 13 C-Acetic Acid Breath Test by Measuring Effects of Loperamide, Morphine, Mosapride, and Itopride on Gastric Emptying in Mice. Biol Pharm Bull. 2008 Oct;31(10):1917-22.

Customs & Trade Information

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Itopride?

The CAS number of Itopride is 122898-67-3.

What are the molecular formula and molecular weight of Itopride?

Itopride has molecular formula C20H26N2O4 and molecular weight 358.431 g/mol.

What are the upstream and downstream products of Itopride?

For Itopride, Upstream Products: N-(4-hydroxybenzyl)-3,4-dimethoxybenzamide, 2-Chloro-N,N-dimethylethanamine, 4-[2-(dimethylamino)ethoxy]benzylamine; Downstream Products: Itopride hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Itopride (CAS 122898-67-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33478-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.