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L-Buthionine sulfoximine

Also known as: L-Buthionine-(S,R)-sulfoximine, L-BSO, Buthionine sulfoximine, L-Buthionine-S,R-sulfoximine, L-Buthionine S,R-sulphoximine, L-Buthionine sulfoximine, Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, (2S)-

L-Buthionine sulfoximine (CAS 83730-53-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H18N2O3S and a molecular weight of 222.305 g/mol. Key properties include a melting point of 224-228ºC (dec.), a boiling point of 382.3±52.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 185.0±30.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
83730-53-4
Jingsj CID
J-33376-2
Molecular Formula
C8H18N2O3S
Molecular Weight
222.305 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point224-228ºC (dec.)
Boiling Point382.3±52.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point185.0±30.7 °C
Exact Mass222.103806
PSA112.62000
LogP0.22
Vapor Pressure0.0±1.9 mmHg at 25°C
Refractive Index1.538

Activity & Biological Data

Targetγ-glutamylcysteine synthetase[1].
Additional Information[1]. Fruehauf JP, et al. Selective and synergistic activity of L-S,R-buthionine sulfoximine on malignant melanoma is accompanied by decreased expression of glutathione-S-transferase. Pigment Cell Res. 1997 Aug;10(4):236-49. [2]. Reliene R, et al. Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. Carcinogenesis. 2006 Feb;27(2):240-4.

Customs & Trade Information

HS Code2925290090
Summary2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Frequently Asked Questions

What is the CAS number of L-Buthionine sulfoximine?

The CAS number of L-Buthionine sulfoximine is 83730-53-4.

What are the molecular formula and molecular weight of L-Buthionine sulfoximine?

L-Buthionine sulfoximine has molecular formula C8H18N2O3S and molecular weight 222.305 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "L-Buthionine sulfoximine (CAS 83730-53-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-33376-2 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.