7-Acetoxy-4-methylcoumarin

Also known as: 4-methylumbelliferyl acetate, 4-Methylumbelliferyl Acetate, 4-MU-acetate, MUB acetate, acetic acid 4-methyl-2-oxo-2H-chromen-7-yl ester, 4-methyl-2-oxo-2H-chromen-7-yl acetate, 7-(acetyloxy)-4-methyl-2H-1-benzopyran-2-one, 4-methyl-7-acetoxycoumarin, 7-hydroxy-4-methylcoumarin acetate

7-Acetoxy-4-methylcoumarin (CAS 2747-05-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C12H10O4 and a molecular weight of 218.20500 g/mol. Key properties include a melting point of 149-150 °C(lit.), a boiling point of 371.4ºC at 760mmHg, a density of 1.263g/cm3 and a flash point of 191.5ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 2747-05-9
Jingsj CID: J-32713-9
Molecular Formula: C₁₂H₁₀O₄
Molecular Weight: 218.20500 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	149-150 °C(lit.)
Boiling Point	371.4ºC at 760mmHg
Density	1.263g/cm3
Flash Point	191.5ºC
Exact Mass	218.05800
PSA	56.51000
LogP	2.02670
Vapor Pressure	8.68E-06mmHg at 25°C
Refractive Index	1.588

GHS Safety & Compliance

IrritantSignal word: Warning

H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information	[1]. Feuer, G, et al. Induction of drug-metabolizing enzymes of rat liver by derivatives of coumarin. Canadian Journal of Physiology and Pharmacology, 48(4), 232–240. [2]. Raj HG, et al. Mechanism of biochemical action of substituted benzopyran-2-ones. Part 8: Acetoxycoumarin: protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom. Bioorg Med Chem. 2001 May;9(5):1085-9.

Additional Information

[1]. Feuer, G, et al. Induction of drug-metabolizing enzymes of rat liver by derivatives of coumarin. Canadian Journal of Physiology and Pharmacology, 48(4), 232–240. [2]. Raj HG, et al. Mechanism of biochemical action of substituted benzopyran-2-ones. Part 8: Acetoxycoumarin: protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom. Bioorg Med Chem. 2001 May;9(5):1085-9.

Customs & Trade Information

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 7-Acetoxy-4-methylcoumarin?

The CAS number of 7-Acetoxy-4-methylcoumarin is 2747-05-9.

What are the molecular formula and molecular weight of 7-Acetoxy-4-methylcoumarin?

7-Acetoxy-4-methylcoumarin has molecular formula C12H10O4 and molecular weight 218.20500 g/mol.

Is 7-Acetoxy-4-methylcoumarin hazardous?

7-Acetoxy-4-methylcoumarin has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 7-Acetoxy-4-methylcoumarin?

For 7-Acetoxy-4-methylcoumarin, Upstream Products: 4-Methylumbelliferone, acetic acid, Acetyl chloride; Downstream Products: 6-acetyl-7-hydroxy-4-methyl-2H-chromen-2-one, 8-Acetyl-7-hydroxy-4-methylcoumarin, 8-acetyl-7-hydroxycoumarin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "7-Acetoxy-4-methylcoumarin (CAS 2747-05-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-32713-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.