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Dihydrokainic acid

Also known as: dihydrokainate, (2S,3S,4R)-2-carboxy-4-isopropyl-3-pyrrolidineacetic acid, (2S,3S,4R)-3-(carboxymethyl)-4-isopropyl-proline, (2S,3S,4R)-3-(carboxymethyl)-4-propan-2-yl-2-pyrrolidinecarboxylic acid, (2S,3S,4R)-3-(carboxymethyl)-4-propan-2-ylpyrrolidine-2-carboxylic acid, 2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid, 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethyl)-, (2S,3S,4R)-, (2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methylethyl)-3-pyrrolidineacetic acid, (3S,4R)-3-(carboxymethyl)-4-propan-2-yl-L-proline, DHK, OPiKa-1

Dihydrokainic acid (CAS 52497-36-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C10H17NO4 and a molecular weight of 215.25 g/mol. Key properties include a melting point of 285 °C (dec.), a boiling point of 416.6ºC at 760mmHg and a density of 1.187g/cm3. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
52497-36-6
Jingsj CID
J-30965-9
Molecular Formula
C10H17NO4
Molecular Weight
215.25 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point285 °C (dec.)
Boiling Point416.6ºC at 760mmHg
Density1.187g/cm3
Exact Mass215.11600
PSA86.63000
LogP0.73470
Refractive Index1.492

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H312 — Harmful in contact with skin
  • H332 — Harmful if inhaled

Activity & Biological Data

TargetGLT1[1]
Additional Information[1]. Tian SW, et al. Glutamate transporter GLT1 inhibitor dihydrokainic acid impairs novel object recognition memory performance in mice. Physiol Behav. 2019 Feb 1;199:28-32. [2]. Butcher SP, et al. On the epileptogenic effects of kainic acid and dihydrokainic acid in the dentate gyrus of the rat. Neuropharmacology. 1988 Apr;27(4):375-81.

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Dihydrokainic acid?

The CAS number of Dihydrokainic acid is 52497-36-6.

What are the molecular formula and molecular weight of Dihydrokainic acid?

Dihydrokainic acid has molecular formula C10H17NO4 and molecular weight 215.25 g/mol.

Is Dihydrokainic acid hazardous?

Dihydrokainic acid has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.

What are the upstream and downstream products of Dihydrokainic acid?

For Dihydrokainic acid, Upstream Products: Kainic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Dihydrokainic acid (CAS 52497-36-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30965-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.