(S)-(-)-5-Fluorowillardiine

Also known as: (S)-(-)-5-Fluorowillardiine, 3-(5-fluorouracil-1-yl)-L-alanine, 5-Fluorowillardiine, Fluoro-willardiine, (2S)-2-amino-3-(5-fluoro-2,4-dioxopyrimidin-1-yl)propanoic acid, 1mqi, FWD, Tocris-0306

(S)-(-)-5-Fluorowillardiine (CAS 140187-23-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C7H8FN3O4 and a molecular weight of 217.15500 g/mol. Key properties include a melting point of 235ºC and a density of 1.64 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 140187-23-1
Jingsj CID: J-30961-9
Molecular Formula: C₇H₈FN₃O₄
Molecular Weight: 217.15500 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	235ºC
Density	1.64 g/cm3
Exact Mass	217.05000
PSA	118.18000
Refractive Index	1.601
Storage Conditions	Store at RT

Activity & Biological Data

Additional Information	[1]. Hawkinson JE, et al. Effects of thiocyanate and AMPA receptor ligands on (S)-5-fluorowillardiine, (S)-AMPA and (R,S)-AMPA binding. Eur J Pharmacol. 1997 Jun 25;329(2-3):213-21. [2]. Kessler M, et al. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain Res. 2006 Mar 3;1076(1):25-41. [3]. Rembach A, et al. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS. J Neurosci Res. 2004 Aug 15;77(4):573-82.

Additional Information

[1]. Hawkinson JE, et al. Effects of thiocyanate and AMPA receptor ligands on (S)-5-fluorowillardiine, (S)-AMPA and (R,S)-AMPA binding. Eur J Pharmacol. 1997 Jun 25;329(2-3):213-21. [2]. Kessler M, et al. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain Res. 2006 Mar 3;1076(1):25-41. [3]. Rembach A, et al. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS. J Neurosci Res. 2004 Aug 15;77(4):573-82.

Frequently Asked Questions

What is the CAS number of (S)-(-)-5-Fluorowillardiine?

The CAS number of (S)-(-)-5-Fluorowillardiine is 140187-23-1.

What are the molecular formula and molecular weight of (S)-(-)-5-Fluorowillardiine?

(S)-(-)-5-Fluorowillardiine has molecular formula C7H8FN3O4 and molecular weight 217.15500 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "(S)-(-)-5-Fluorowillardiine (CAS 140187-23-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30961-9 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.