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(S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid

Also known as: (S)-AMPA, L-AMPA, (αS)-α-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid, 4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-, (S)-, (S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid, (S)-α-Amino-3-(3-hydroxy-5-methyl-4-isoxazol)propionic acid, (2S)-2-amino-3-(5-methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid, AMQ

(S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid (CAS 83643-88-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C7H10N2O4 and a molecular weight of 186.165 g/mol. Key properties include a melting point of 118-122 °C(lit.), a boiling point of 425.6±45.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 211.2±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
83643-88-3
Jingsj CID
J-30956-3
Molecular Formula
C7H10N2O4
Molecular Weight
186.165 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point118-122 °C(lit.)
Boiling Point425.6±45.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point211.2±28.7 °C
Exact Mass186.064056
PSA109.58000
LogP-0.44
Vapor Pressure0.0±1.1 mmHg at 25°C
Refractive Index1.579

Activity & Biological Data

Additional Information[1]. J A Larm, et al. (S)-5-fluorowillardiine-mediated neurotoxicity in cultured murine cortical neurones occurs via AMPA and kainate receptors. Eur J Pharmacol. 1996 Oct 24;314(1-2):249-54. [2]. B Ebert, et al. Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA. Neurochem Int. 1994 Jun;24(6):507-15. [3]. J W Brooks, et al. (S)-AMPA inhibits electrically evoked calcitonin gene-related peptide (CGRP) release from the rat dorsal horn: reversal by cannabinoid receptor antagonist SR141716A. Neurosci Lett. 2004 Nov 30;372(1-2):85-8. [4]. J A Larm, et al. Apoptosis induced via AMPA-selective glutamate receptors in cultured murine cortical neurons. J Neurochem. 1997 Aug;69(2):617-22.

Customs & Trade Information

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of (S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid?

The CAS number of (S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid is 83643-88-3.

What are the molecular formula and molecular weight of (S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid?

(S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid has molecular formula C7H10N2O4 and molecular weight 186.165 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "(S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid (CAS 83643-88-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30956-3 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.