Luzindole

Also known as: N-Acetyl-2-benzyltryptamine, N-0774, N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide, N-[2-[2-(phenylmethyl)-1H-indol-3-yl]ethyl]acetamide, 2-Benzyl-N-acetyltryptamine

Luzindole (CAS 117946-91-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C19H20N2O and a molecular weight of 292.375 g/mol. Key properties include a melting point of 44-46°C, a boiling point of 559.6±38.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 292.2±26.8 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 117946-91-5
Jingsj CID: J-30941-7
Molecular Formula: C₁₉H₂₀N₂O
Molecular Weight: 292.375 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	44-46°C
Boiling Point	559.6±38.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	292.2±26.8 °C
Exact Mass	292.157562
PSA	44.89000
LogP	3.04
Vapor Pressure	0.0±1.5 mmHg at 25°C
Refractive Index	1.632
Additional Property	DMSO: 5 mg/mL

Activity & Biological Data

Target	Ki :10.2 nM (human MT2), 158 nM (human MT1)[1]
Additional Information	[1]. Dubocovich ML, et al. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355(3):365-75. [2]. Constantinescu CS, et al. Luzindole, a melatonin receptor antagonist, suppresses experimental autoimmune encephalomyelitis. Pathobiology. 1997;65(4):190-4. [3]. Dubocovich ML Antidepressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in the mouse behavioral despair test. Eur J Pharmacol. 1990 Jul 3;182(2):313-25.

Target

Ki :10.2 nM (human MT2), 158 nM (human MT1)[1]

Additional Information

[1]. Dubocovich ML, et al. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355(3):365-75. [2]. Constantinescu CS, et al. Luzindole, a melatonin receptor antagonist, suppresses experimental autoimmune encephalomyelitis. Pathobiology. 1997;65(4):190-4. [3]. Dubocovich ML Antidepressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in the mouse behavioral despair test. Eur J Pharmacol. 1990 Jul 3;182(2):313-25.

Frequently Asked Questions

What is the CAS number of Luzindole?

The CAS number of Luzindole is 117946-91-5.

What are the molecular formula and molecular weight of Luzindole?

Luzindole has molecular formula C19H20N2O and molecular weight 292.375 g/mol.

What are the upstream and downstream products of Luzindole?

For Luzindole, Upstream Products: tryptamine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Luzindole (CAS 117946-91-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30941-7 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.