2-Thiouracil
Also known as: 2,3-dihydro-2-thioxo-4(1H)-pyrimidinone, 2-MERCAPTO-4-HYDROXYPYRIMIDINE, 2-MERCAPTO-4-PYRIMIDONE, 2-Mercapto-4-hydroxypyrimidine, 2-Mercapto-4-pyrimidone, 2-Sulfanylpyrimidin-4(3H)-one, 2-TU, 2-Thioxo-2,3-dihydro-4(1H)-pyrimidinone, 2-Thioxo-2,3-dihydropyrimidin-4(1H)-one, 2-sulfanylpyrimidin-4-ol, 2-thio-uraci, 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo-, 4(3H)-pyrimidinone, 2-mercapto-, 4-HYDROXY-2-MERCAPTOPYRIMIDINE, 4-HYDROXY-2-THIOPYRIMIDINE, 4-Hydroxy-2-mercaptopyrimidine, 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine, DERACIL, Nobilen, THIURACIL
2-Thiouracil (CAS 141-90-2) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C4H4N2OS and a molecular weight of 128.152 g/mol. Key properties include a melting point of >300 °C(lit.), a boiling point of 337.2ºC at 760mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 157.7ºC. It is classified under GHS with signal word Warning and hazard statements H351 — Suspected of causing cancer. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.
- CAS No.
- 141-90-2
- Jingsj CID
- J-30482-5
- Molecular Formula
- C4H4N2OS
- Molecular Weight
- 128.152 g/mol
- Category
- Pharma Intermediates
- Last updated
- 11/3/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | >300 °C(lit.) |
|---|---|
| Boiling Point | 337.2ºC at 760mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 157.7ºC |
| Exact Mass | 128.004440 |
| PSA | 80.74000 |
| LogP | -0.28 |
| Vapor Pressure | 5.45E-05mmHg at 25°C |
| Refractive Index | 1.678 |
| Additional Property | 0.5 g/L |
GHS Safety & Compliance
- H351 — Suspected of causing cancer
Activity & Biological Data
| Additional Information | [1]. Palumbo, A., M. d'Ischia, and F.A. Cioffi, 2-thiouracil is a selective inhibitor of neuronal nitric oxide synthase antagonising tetrahydrobiopterin-dependent enzyme activation and dimerisation. FEBS Lett, 2000. 485(2-3): p. 109-12. [2]. Napolitano, A., et al., Mechanism of selective incorporation of the melanoma seeker 2-thiouracil into growing melanin. J Med Chem, 1996. 39(26): p. 5192-201. [3]. Nagasaka, A. and H. Hidaka, Effect of antithyroid agents 6-propyl-2-thiouracil and 1-mehtyl-2-mercaptoimidazole on human thyroid iodine peroxidase. J Clin Endocrinol Metab, 1976. 43(1): p. 152-8. |
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Customs & Trade Information
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 2-Thiouracil?
The CAS number of 2-Thiouracil is 141-90-2.
What are the molecular formula and molecular weight of 2-Thiouracil?
2-Thiouracil has molecular formula C4H4N2OS and molecular weight 128.152 g/mol.
Is 2-Thiouracil hazardous?
2-Thiouracil has GHS signal word Warning and hazard statements H351 — Suspected of causing cancer.
What are the upstream and downstream products of 2-Thiouracil?
For 2-Thiouracil, Upstream Products: 4-Amino-2-mercaptopyrimidine, Ethyl 3,3-diethoxypropionate, 1,3-Dimethyluracil; Downstream Products: 2,4-Dichloropyrimidine, 4-Hydroxy-2-phenylpyrimidine, Thymine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-Thiouracil (CAS 141-90-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30482-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.