Memantine hydrochloride

Also known as: Memantine HCl, 1-Amino-3,5-dimethyladamantane hydrochloride, 3,5-Dimethyl-1-adamantanamine hydrochloride, 3,5-Dimethyladamantan-1-amine hydrochloride, 3,5-Dimethyltricyclo[3.3.1.1]decan-1-amine hydrochloride, 1,3-Dimethyl-5-aminoadamantane hydrochloride, 1,3-Dimethylaminoadamantane hydrochloride, 3,5-Dimethylamantadine hydrochloride, Akatinol, Axura, Ebixia, Ebixza

Memantine hydrochloride (CAS 41100-52-1) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C12H22ClN and a molecular weight of 215.763 g/mol. Key properties include a melting point of 292 °C, a boiling point of 239.8ºC at 760 mmHg and a flash point of 92.3ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 41100-52-1
Jingsj CID: J-3023-9
Molecular Formula: C₁₂H₂₂ClN
Molecular Weight: 215.763 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	292 °C
Boiling Point	239.8ºC at 760 mmHg
Flash Point	92.3ºC
Exact Mass	215.144073
PSA	26.02000
LogP	4.19640

Activity & Biological Data

Additional Information	[1]. Robinson, D.M. and G.M. Keating, Memantine: a review of its use in Alzheimer's disease. Drugs, 2006. 66(11): p. 1515-34. [2]. Chen, H.S., et al., Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci, 1992. 12(11): p. 4427-36. [3]. Chen, H.S. and S.A. Lipton, Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism. J Physiol, 1997. 499 ( Pt 1): p. 27-46.

Additional Information

[1]. Robinson, D.M. and G.M. Keating, Memantine: a review of its use in Alzheimer's disease. Drugs, 2006. 66(11): p. 1515-34. [2]. Chen, H.S., et al., Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci, 1992. 12(11): p. 4427-36. [3]. Chen, H.S. and S.A. Lipton, Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism. J Physiol, 1997. 499 ( Pt 1): p. 27-46.

Customs & Trade Information

HS Code	2921300090
Summary	2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Memantine hydrochloride?

The CAS number of Memantine hydrochloride is 41100-52-1.

What are the molecular formula and molecular weight of Memantine hydrochloride?

Memantine hydrochloride has molecular formula C12H22ClN and molecular weight 215.763 g/mol.

What are the upstream and downstream products of Memantine hydrochloride?

For Memantine hydrochloride, Upstream Products: 1-Acetamido-3,5-dimethyladamantane, N-(3,5-Dimethyladamantan-1-yl)formamide, Memantine; Downstream Products: Memantine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Memantine hydrochloride (CAS 41100-52-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-3023-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.