ambenonium chloride

Also known as: Ambenonium Dichloride, Ambestigmin, Mytelase, WIN 8077, N,N'-[(1,2-dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis[2-chloro-N,N-diethylbenzenemethanaminium] dichloride

ambenonium chloride (CAS 115-79-7) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C28H42Cl4N4O2 and a molecular weight of 608.47100 g/mol. Key property: a melting point of 196-199°. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 115-79-7
Jingsj CID: J-30225-2
Molecular Formula: C₂₈H₄₂Cl₄N₄O₂
Molecular Weight: 608.47100 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	196-199°
Exact Mass	606.20600
PSA	58.20000

Activity & Biological Data

Target	Acetylcholinesterase:0.7 nM (IC50) Acetylcholinesterase:0.12 nM (Ki) Butyrylcholinesterase:7 μM (IC50)
Additional Information	[1]. Hodge AS, et al. Ambenonium is a rapidly reversible noncovalent inhibitor of acetylcholinesterase, with one of the highest known affinities. Mol Pharmacol. 1992 May. 41(5):937-42. [2]. Komloova M, et al. Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment. Bioorg Med Chem Lett. 2011 Apr 15. 21(8):2505-9. [3]. Hazama R, et al. Effects of long-term administration of ambenonium chloride on motor end-plate fine structure and acetylcholine receptor in rat. J Neurol Sci. 1981 Jul. 51(1):69-79.

Target

Acetylcholinesterase:0.7 nM (IC50) Acetylcholinesterase:0.12 nM (Ki) Butyrylcholinesterase:7 μM (IC50)

Additional Information

[1]. Hodge AS, et al. Ambenonium is a rapidly reversible noncovalent inhibitor of acetylcholinesterase, with one of the highest known affinities. Mol Pharmacol. 1992 May. 41(5):937-42. [2]. Komloova M, et al. Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment. Bioorg Med Chem Lett. 2011 Apr 15. 21(8):2505-9. [3]. Hazama R, et al. Effects of long-term administration of ambenonium chloride on motor end-plate fine structure and acetylcholine receptor in rat. J Neurol Sci. 1981 Jul. 51(1):69-79.

Frequently Asked Questions

What is the CAS number of ambenonium chloride?

The CAS number of ambenonium chloride is 115-79-7.

What are the molecular formula and molecular weight of ambenonium chloride?

ambenonium chloride has molecular formula C28H42Cl4N4O2 and molecular weight 608.47100 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "ambenonium chloride (CAS 115-79-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-30225-2 (accessed 2026-11-07).

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