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4-Fluorophenylacetonitrile

Also known as: 4-Fluorobenzyl cyanide, p-Fluorobenzyl cyanide, p-Fluorophenylacetonitrile, 4-Fluorobenzeneacetonitrile, (4-Fluorophenyl)acetonitrile, 4-Fluorobenzylnitrile, p-Fluorobenzyl nitrile

4-Fluorophenylacetonitrile (CAS 459-22-3) is a compound in the Aromatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C8H6FN and a molecular weight of 135.138 g/mol. Key properties include a melting point of 86ºC, a boiling point of 234.2±0.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 108.3±0.0 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
459-22-3
Jingsj CID
J-2936-7
Molecular Formula
C8H6FN
Molecular Weight
135.138 g/mol
Category
Aromatic Hydrocarbons
Last updated
8/21/2026

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Physicochemical Properties

Melting Point86ºC
Boiling Point234.2±0.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point108.3±0.0 °C
Exact Mass135.048431
PSA23.79000
LogP1.50
Vapor Pressure0.1±0.4 mmHg at 25°C
Refractive Index1.508

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H312 — Harmful in contact with skin
  • H332 — Harmful if inhaled
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2926909090
SummaryHS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4-Fluorophenylacetonitrile?

The CAS number of 4-Fluorophenylacetonitrile is 459-22-3.

What are the molecular formula and molecular weight of 4-Fluorophenylacetonitrile?

4-Fluorophenylacetonitrile has molecular formula C8H6FN and molecular weight 135.138 g/mol.

Is 4-Fluorophenylacetonitrile hazardous?

4-Fluorophenylacetonitrile has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.

What are the upstream and downstream products of 4-Fluorophenylacetonitrile?

For 4-Fluorophenylacetonitrile, Upstream Products: (Trimethylsilyl)acetonitrile, 1-Bromo-4-fluorobenzene, 4-Isoxazoleboronic acid pinacol ester; Downstream Products: 2-(4-Fluorophenyl)-1-phenylethanone, 4-Cyano-4-(4-fluorophenyl)cyclohexanone, 4-Fluorophenylacetic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-Fluorophenylacetonitrile (CAS 459-22-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2936-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.