2-Cyanopyrimidine
Also known as: 2-Pyrimidinecarbonitrile, Pyrimidine-2-carbonitrile, 2-Cynopyrimidine, 2-Cyanpyrimidine, 2-CPY, 2CPM, Pyrimidin-2-carbonitril
2-Cyanopyrimidine (CAS 14080-23-0) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C5H3N3 and a molecular weight of 105.097 g/mol. Key properties include a melting point of 40-44 °C(lit.), a boiling point of 250.7±23.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 97.2±7.8 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed and H317 — May cause an allergic skin reaction. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 14080-23-0
- Jingsj CID
- J-28651-1
- Molecular Formula
- C5H3N3
- Molecular Weight
- 105.097 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 40-44 °C(lit.) |
|---|---|
| Boiling Point | 250.7±23.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 97.2±7.8 °C |
| Exact Mass | 105.032700 |
| PSA | 49.57000 |
| LogP | -0.31 |
| Vapor Pressure | 0.0±0.5 mmHg at 25°C |
| Refractive Index | 1.541 |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H317 — May cause an allergic skin reaction
Activity & Biological Data
| Target | IC50: 170 nM (cysteine protease cathepsin K)[1] |
|---|---|
| Additional Information | [1]. Altmann E, et al. 2-Cyano-pyrimidines: a new chemotype for inhibitors of the cysteine protease cathepsin K. J Med Chem. 2007 Feb 22;50(4):591-4. |
Customs & Trade Information
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 2-Cyanopyrimidine?
The CAS number of 2-Cyanopyrimidine is 14080-23-0.
What are the molecular formula and molecular weight of 2-Cyanopyrimidine?
2-Cyanopyrimidine has molecular formula C5H3N3 and molecular weight 105.097 g/mol.
Is 2-Cyanopyrimidine hazardous?
2-Cyanopyrimidine has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H317 — May cause an allergic skin reaction.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-Cyanopyrimidine (CAS 14080-23-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28651-1 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.