Nevirapine
Also known as: 11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-Cyclopropyl-4-methyl-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6(11H)-one, 11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-methyl-, AIDS005653, BI-RG-587, D00435, MFCD00866928, Viramune
Nevirapine (CAS 129618-40-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H14N4O and a molecular weight of 266.298 g/mol. Key properties include a melting point of 247°C, a boiling point of 415.4±45.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 205.0±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 129618-40-2
- Jingsj CID
- J-2827-3
- Molecular Formula
- C15H14N4O
- Molecular Weight
- 266.298 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 247°C |
|---|---|
| Boiling Point | 415.4±45.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 205.0±28.7 °C |
| Exact Mass | 266.116760 |
| PSA | 63.57000 |
| LogP | 2.03 |
| Vapor Pressure | 0.0±1.0 mmHg at 25°C |
| Refractive Index | 1.672 |
| Storage Conditions | -20°C Freezer |
Activity & Biological Data
| Target | Ki: 270 μM (HIV-1 reverse transcriptase)[1] |
|---|---|
| Additional Information | [1]. Erickson DA, et al. Characterization of the in vitro biotransformation of the HIV-1 reverse transcriptase inhibitornevirapine by human hepatic cytochromes P-450. Drug Metab Dispos. 1999 Dec;27(12):1488-95. [2]. Dong JJ, et al. In vitro evaluation of the therapeutic potential of nevirapine in treatment of human thyroid anaplastic carcinoma. Mol Cell Endocrinol. 2013 May 6;370(1-2):113-8. [3]. Merluzzi VJ, et al. Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor. Science. 1990 Dec 7;250(4986):1411-3. [4]. Riska PS, et al. Biotransformation of nevirapine, a non-nucleoside HIV-1 reverse transcriptase inhibitor, in mice, rats, rabbits, dogs, monkeys, and chimpanzees. Drug Metab Dispos. 1999 Dec;27(12):1434-47. [5]. Onasanwo SA, et al. Evaluation of anti-ulcerogenic and ulcer-healing activities of nevirapine in rats. Afr J Med Med Sci. 2015 Sep;44(3):251-9. |
Customs & Trade Information
| HS Code | 2934994000 |
|---|---|
| Summary | 2934994000. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Nevirapine?
The CAS number of Nevirapine is 129618-40-2.
What are the molecular formula and molecular weight of Nevirapine?
Nevirapine has molecular formula C15H14N4O and molecular weight 266.298 g/mol.
What are the upstream and downstream products of Nevirapine?
For Nevirapine, Upstream Products: N-(2-chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide, 2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide, Cyclopropylamine; Downstream Products: 2-(Cyclopropylamino)nicotinic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Nevirapine (CAS 129618-40-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2827-3 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.