calpeptin

Also known as: BENZYLOXYCARBONYLDIPEPTIDYL ALDEHYDE, BENZYLOXYCARBONYLLEUCYL-NORLEUCINAL, Calpeptin - CAS 117591-20-5 - Calbiochem, Calpeptin,N-Benzyloxycarbonyl-L-leucylnorleucinal, CalpeptinN-Benzyloxycarbonyl-L-leucyl-norleucinal, Carbamic acid, N-[(1S)-1-[[[(1S)-1-formylpentyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester, MFCD00155623, N-BENZYLOXYCARBONYL-L-LEUCYL-NORLEUCINAL, N-BENZYLOXYCARBONYL-L-LEUCYLNORLEUCINAL, N-Benzyloxycarbonyl-L-leucylnorieucinal Z-Leu-Nle-CHO, N-CBZ-L-LEUCYL-NORLEUCINAL, N-[(Benzyloxy)carbonyl]-N-[(2S)-1-oxo-2-hexanyl]-L-leucinamide, N-[(benzyloxy)carbonyl]-N-[(2S)-1-oxohexan-2-yl]-L-leucinamide, N-benzyloxycarbonyl-L-leucyl-L-norleucinal, Z-LEU-NLE-CHO, Z-LEU-NLE-OH, Z-LEU-NORLEUCINAL, Z-Leu-Nle-H, N-Benzyloxycarbonyl-L-leucylnorleucinal, Z-Leu-norleucinal

calpeptin (CAS 117591-20-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C20H30N2O4 and a molecular weight of 362.463 g/mol. Key properties include a melting point of 60-75 °C, a boiling point of 550.7±45.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 286.8±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 117591-20-5
Jingsj CID: J-28108-9
Molecular Formula: C₂₀H₃₀N₂O₄
Molecular Weight: 362.463 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	60-75 °C
Boiling Point	550.7±45.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	286.8±28.7 °C
Exact Mass	362.220551
PSA	84.50000
LogP	4.37
Vapor Pressure	0.0±1.5 mmHg at 25°C
Refractive Index	1.508

Activity & Biological Data

Target	ID50: 40 nM (Calpain I in human platelets)[1]. Cthepsin K[2]
Additional Information	[1]. Tsujinaka T, et al. Synthesis of a new cell penetrating calpain inhibitor (calpeptin). Biochem Biophys Res Commun. 1988 Jun 30;153(3):1201-8. [2]. Catalano JG, et al. Design of small molecule ketoamide-based inhibitors of cathepsin K. Bioorg Med Chem Lett. 2004 Feb 9;14(3):719-22. [3]. Tabata C, et al. The calpain inhibitor calpeptin prevents pulmonary fibrosis in mice. Clin Exp Immunol. 2010 Dec;162(3):560-7.

Target

ID50: 40 nM (Calpain I in human platelets)[1]. Cthepsin K[2]

Additional Information

[1]. Tsujinaka T, et al. Synthesis of a new cell penetrating calpain inhibitor (calpeptin). Biochem Biophys Res Commun. 1988 Jun 30;153(3):1201-8. [2]. Catalano JG, et al. Design of small molecule ketoamide-based inhibitors of cathepsin K. Bioorg Med Chem Lett. 2004 Feb 9;14(3):719-22. [3]. Tabata C, et al. The calpain inhibitor calpeptin prevents pulmonary fibrosis in mice. Clin Exp Immunol. 2010 Dec;162(3):560-7.

Frequently Asked Questions

What is the CAS number of calpeptin?

The CAS number of calpeptin is 117591-20-5.

What are the molecular formula and molecular weight of calpeptin?

calpeptin has molecular formula C20H30N2O4 and molecular weight 362.463 g/mol.

What are the upstream and downstream products of calpeptin?

For calpeptin, Upstream Products: N-[(Benzyloxy)carbonyl]-L-leucine, (S)-(+)-2-Amino-1-hexanol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "calpeptin (CAS 117591-20-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28108-9 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.