Suramin sodium

Also known as: Suramin hexasodium, Suramin sodium salt, Sodium suramin, Naphuride, Germanin, Antrypol, Bayer 205, Moranyl, Fourneau 309, 309F, NF 060, CI 1003, Hexasodium 8,8'-{carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]}di(1,3,5-naphthalenetrisulfonate), Hexasodium sym-Bis(m-aminobenzoyl-m-amino-p-methylbenzoyl-1-naphthylamino-4,6,8-trisulfonate) Carbamide, 1,3,5-Naphthalenetrisulfonic acid, 8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-, hexasodium salt, Suramine sodium

Suramin sodium (CAS 129-46-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C51H34N6Na6O23S6 and a molecular weight of 1429.171 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 129-46-4
Jingsj CID: J-28097-7
Molecular Formula: C₅₁H₃₄N₆Na₆O₂₃S₆
Molecular Weight: 1429.171 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	1427.938599
PSA	551.01000
LogP	11.61040
Storage Conditions	0-6°C

Activity & Biological Data

Target	IC50: 5 μM (DNA topoisomerase II)[3]
Additional Information	[1]. Jindal HK, et al. Suramin affects DNA synthesis in HeLa cells by inhibition of DNA polymerases. Cancer Res. 1990 Dec 15;50(24):7754-7. [2]. Nautiyal A, et al. Suramin is a potent and selective inhibitor of Mycobacterium tuberculosis RecA protein and the SOS response: RecA as a potential target for antibacterial drug discovery. J Antimicrob Chemother. 2014 Jul;69(7):1834-43. [3]. Bojanowski K, et al. Suramin is an inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcomacells. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):3025-9. [4]. Izikki M, et al. The beneficial effect of suramin on monocrotaline-induced pulmonary hypertension in rats. PLoS One. 2013 Oct 15;8(10):e77073.

Target

IC50: 5 μM (DNA topoisomerase II)[3]

Additional Information

[1]. Jindal HK, et al. Suramin affects DNA synthesis in HeLa cells by inhibition of DNA polymerases. Cancer Res. 1990 Dec 15;50(24):7754-7. [2]. Nautiyal A, et al. Suramin is a potent and selective inhibitor of Mycobacterium tuberculosis RecA protein and the SOS response: RecA as a potential target for antibacterial drug discovery. J Antimicrob Chemother. 2014 Jul;69(7):1834-43. [3]. Bojanowski K, et al. Suramin is an inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcomacells. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):3025-9. [4]. Izikki M, et al. The beneficial effect of suramin on monocrotaline-induced pulmonary hypertension in rats. PLoS One. 2013 Oct 15;8(10):e77073.

Frequently Asked Questions

What is the CAS number of Suramin sodium?

The CAS number of Suramin sodium is 129-46-4.

What are the molecular formula and molecular weight of Suramin sodium?

Suramin sodium has molecular formula C51H34N6Na6O23S6 and molecular weight 1429.171 g/mol.

What are the upstream and downstream products of Suramin sodium?

For Suramin sodium, Upstream Products: 4-Methyl-3-nitrobenzoyl chloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Suramin sodium (CAS 129-46-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28097-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.