Propofol
Also known as: 2,6-Diisopropylphenol, 2,6-Bis(1-methylethyl)phenol, 2,6-di(propan-2-yl)phenol, Disoprofol, Diprivan, Disoprivan, Fresofol, Propofolum
Propofol (CAS 2078-54-8) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C12H18O and a molecular weight of 178.271 g/mol. Key properties include a melting point of 18 °C(lit.), a boiling point of 256.0±0.0 °C at 760 mmHg, a density of 0.9±0.1 g/cm3 and a flash point of 107.5±7.2 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 2078-54-8
- Jingsj CID
- J-28079-6
- Molecular Formula
- C12H18O
- Molecular Weight
- 178.271 g/mol
- Category
- Alcohols
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 18 °C(lit.) |
|---|---|
| Boiling Point | 256.0±0.0 °C at 760 mmHg |
| Density | 0.9±0.1 g/cm3 |
| Flash Point | 107.5±7.2 °C |
| Exact Mass | 178.135757 |
| PSA | 20.23000 |
| LogP | 4.16 |
| Vapor Pressure | 0.0±0.5 mmHg at 25°C |
| Refractive Index | 1.513 |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | GABAA[1] |
|---|---|
| Additional Information | [1]. R Nadeson, et al. Antinociceptive Properties of Propofol: Involvement of Spinal Cord Gamma-Aminobutyric acid(A) Receptors. J Pharmacol Exp Ther . 1997 Sep;282(3):1181-6. |
Customs & Trade Information
| HS Code | 2907199090 |
|---|---|
| Summary | 2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Propofol?
The CAS number of Propofol is 2078-54-8.
What are the molecular formula and molecular weight of Propofol?
Propofol has molecular formula C12H18O and molecular weight 178.271 g/mol.
Is Propofol hazardous?
Propofol has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
What are the upstream and downstream products of Propofol?
For Propofol, Upstream Products: 4-Hydroxy-3,5-diisopropylbenzoic acid, 2,6-Diisopropyliodobenzene, platinum; Downstream Products: 4-[(Dimethylamino)methyl]-2,6-diisopropylphenol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Propofol (CAS 2078-54-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28079-6 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.