Calcium folinate
Also known as: Leucovorin calcium, Citrovorum factor calcium salt, 5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt, 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid calcium salt, Folinic acid calcium salt, Calcium folinate hydrate, 5-HCO-H4PteGlu, Calcium (2S)-2-[(4-{[(2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}benzoyl)amino]pentanedioate, L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1)
Calcium folinate (CAS 1492-18-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C20H23CaN7O7 and a molecular weight of 511.501 g/mol. Key property: a melting point of 240-250ºC. It is classified under GHS with signal word Danger and hazard statements H315 — Causes skin irritation, H317 — May cause an allergic skin reaction and H319 — Causes serious eye irritation. It is listed by 1 supplier, from 112.00 to 180.00 CNY. Record last updated Nov 2, 2026.
- CAS No.
- 1492-18-8
- Jingsj CID
- J-2782-9
- Molecular Formula
- C20H23CaN7O7
- Molecular Weight
- 511.501 g/mol
- Category
- Organic Acids
- Last updated
- 11/2/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
In Stock | 99% 5g | ¥560.00 | $16.76 /gBest ¥112.00/g CNY | CN China MOQ 5g | |
In Stock | 99% 1g | ¥180.00 | $26.94 /g ¥180.00/g CNY | CN China MOQ 1g |
Physicochemical Properties
| Melting Point | 240-250ºC |
|---|---|
| Exact Mass | 511.112823 |
| PSA | 198.10000 |
| LogP | 1.41100 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H317 — May cause an allergic skin reaction
- H319 — Causes serious eye irritation
- H334 — May cause allergy or asthma symptoms if inhaled
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Schilsky RL, Ratain MJ. Clinical pharmacokinetics of high-dose leucovorin calcium after intravenous and oral administration. J Natl Cancer Inst. 1990 Sep 5;82(17):1411-5. [2]. Chang WN, Tsai JN, Chen BH, Serine hydroxymethyltransferase isoforms are differentially inhibited by leucovorin: characterization and comparison of recombinant zebrafish serine hydroxymethyltransferases. Drug Metab Dispos. 2007 Nov;35(11):2127-37. [3]. McGuire BW, Sia LL, Haynes JD, Absorption kinetics of orally administered leucovorin calcium. NCI Monogr. 1987;(5):47-56. |
|---|
Customs & Trade Information
| HS Code | 2942000000 |
|---|
Frequently Asked Questions
What is the CAS number of Calcium folinate?
The CAS number of Calcium folinate is 1492-18-8.
What are the molecular formula and molecular weight of Calcium folinate?
Calcium folinate has molecular formula C20H23CaN7O7 and molecular weight 511.501 g/mol.
Which suppliers offer Calcium folinate?
1 supplier(s) listed; reference unit price ¥112.00–180.00 /g.
Is Calcium folinate hazardous?
Calcium folinate has GHS signal word Danger and hazard statements H315 — Causes skin irritation; H317 — May cause an allergic skin reaction; H319 — Causes serious eye irritation.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Calcium folinate (CAS 1492-18-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2782-9 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.