Spirapril

Also known as: (8S)-7-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, (8S-(7(R*(R*)),8R*))-7-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, 1,4-Dithia-7-azaspiro(4,4)nonane-8-carboxylic acid, 7-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, (8S-(7(R*(R*)),8R*))-, Brn 4277924, Espirapril, Renormax, Sandopril, Setrilan, Spiraprilum

Spirapril (CAS 83647-97-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H30N2O5S2 and a molecular weight of 466.61400 g/mol. Key properties include a boiling point of 697.8ºC at 760 mmHg, a density of 1.32 g/cm3 and a flash point of 375.8ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 83647-97-6
Jingsj CID: J-27750-9
Molecular Formula: C₂₂H₃₀N₂O₅S₂
Molecular Weight: 466.61400 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	697.8ºC at 760 mmHg
Density	1.32 g/cm3
Flash Point	375.8ºC
Exact Mass	466.16000
PSA	146.54000
LogP	2.71960
Refractive Index	1.621
Storage Conditions	-20°C

Activity & Biological Data

Additional Information	[1]. Noble S, Sorkin EM. Spirapril. A preliminary review of its pharmacology and therapeutic efficacy in the treatment of hypertension. Drugs. 1995 May;49(5):750-66. [2]. Maul B, et al. Alcohol consumption is controlled by angiotensin II. FASEB J. 2001 Jul;15(9):1640-2. [3]. Olivetti G, et al. Spirapril prevents left ventricular hypertrophy, decreases myocardial damage and promotes angiogenesis in spontaneously hypertensive rats. J Cardiovasc Pharmacol. 1993 Mar;21(3):362-70.

Additional Information

[1]. Noble S, Sorkin EM. Spirapril. A preliminary review of its pharmacology and therapeutic efficacy in the treatment of hypertension. Drugs. 1995 May;49(5):750-66. [2]. Maul B, et al. Alcohol consumption is controlled by angiotensin II. FASEB J. 2001 Jul;15(9):1640-2. [3]. Olivetti G, et al. Spirapril prevents left ventricular hypertrophy, decreases myocardial damage and promotes angiogenesis in spontaneously hypertensive rats. J Cardiovasc Pharmacol. 1993 Mar;21(3):362-70.

Frequently Asked Questions

What is the CAS number of Spirapril?

The CAS number of Spirapril is 83647-97-6.

What are the molecular formula and molecular weight of Spirapril?

Spirapril has molecular formula C22H30N2O5S2 and molecular weight 466.61400 g/mol.

What are the upstream and downstream products of Spirapril?

For Spirapril, Upstream Products: N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanine, (S)-1-((Benzyloxy)carbonyl)-4-oxopyrrolidine-2-carboxylic acid; Downstream Products: Spirapril hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Spirapril (CAS 83647-97-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-27750-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.