Tandospirone
Also known as: Sediel, (3aR,4S,7R,7aS)-rel-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione, (3aα,4β,7β,7aα)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione, 4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aR,4S,7R,7aS)-rel-, Tandospirone [inn:ban], Tandospirone hydrochloride, (1R,2S,6R,7S)-4-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-4-azatricyclo[5.2.1.0]decane-3,5-dione, (1R*,2S*,3R*,4S*)-N-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,3-bicyclo[2.2.1]heptanedicarboximide, [14C]-Tandospirone
Tandospirone (CAS 87760-53-0) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C21H29N5O2 and a molecular weight of 383.487 g/mol. Key properties include a melting point of 112-113.5°, a boiling point of 613.9±65.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 325.1±34.3 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 87760-53-0
- Jingsj CID
- J-27719-6
- Molecular Formula
- C21H29N5O2
- Molecular Weight
- 383.487 g/mol
- Category
- Ketones
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 112-113.5° |
|---|---|
| Boiling Point | 613.9±65.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 325.1±34.3 °C |
| Exact Mass | 383.232117 |
| PSA | 69.64000 |
| LogP | 2.02 |
| Vapor Pressure | 0.0±1.8 mmHg at 25°C |
| Refractive Index | 1.589 |
| Storage Conditions | Store at +4°C |
| Additional Property | DMSO: soluble38mg/mL |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Hamik A, et al. Analysis of tandospirone (SM-3997) interactions with neurotransmitter receptor binding sites. Biol Psychiatry. 1990 Jul 15;28(2):99-109. [2]. Shimizu H, et al. Characterization of the putative anxiolytic SM-3997 recognition sites in rat brain. Life Sci. 1988;42(24):2419-27. [3]. Uehara T, et al. Chronic treatment with tandospirone, a 5-HT1A receptor partial agonist, suppresses footshock stress-induced lactate production in the prefrontal cortex of rats. Pharmacol Biochem Behav. 2013 Nov 15;113:1-6. [4]. Ohmura Y, et al. Tandospirone suppresses impulsive action by possible blockade of the 5-HT1A receptor. J Pharmacol Sci. 2013;122(2):84-92. |
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Frequently Asked Questions
What is the CAS number of Tandospirone?
The CAS number of Tandospirone is 87760-53-0.
What are the molecular formula and molecular weight of Tandospirone?
Tandospirone has molecular formula C21H29N5O2 and molecular weight 383.487 g/mol.
Is Tandospirone hazardous?
Tandospirone has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Tandospirone?
For Tandospirone, Upstream Products: 2-(1-Piperazinyl)pyrimidine, cis-5-Norbornene-exo-2,3-dicarboxylic anhydride, (3aR,4S,7R,7aS)-hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Tandospirone (CAS 87760-53-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-27719-6 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.