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5-Chlorothiophene-2-sulfonamide

Also known as: 5-Chloro-2-thiophenesulfonamide, 2-Chloro-5-sulfamoylthiophene, 2-chlorothiophene-5-sulfonamide, 5-chloro-2-thiophenesulfonamide, 5-chlorothiophene-2-sulfonamide

5-Chlorothiophene-2-sulfonamide (CAS 53595-66-7) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C4H4ClNO2S2 and a molecular weight of 197.663 g/mol. Key properties include a melting point of 113-117 °C(lit.), a boiling point of 366.3±52.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 175.3±30.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
53595-66-7
Jingsj CID
J-26055-9
Molecular Formula
C4H4ClNO2S2
Molecular Weight
197.663 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point113-117 °C(lit.)
Boiling Point366.3±52.0 °C at 760 mmHg
Density1.6±0.1 g/cm3
Flash Point175.3±30.7 °C
Exact Mass196.937195
PSA96.78000
LogP0.94
Vapor Pressure0.0±0.8 mmHg at 25°C
Refractive Index1.621

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2935009090
Summary2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of 5-Chlorothiophene-2-sulfonamide?

The CAS number of 5-Chlorothiophene-2-sulfonamide is 53595-66-7.

What are the molecular formula and molecular weight of 5-Chlorothiophene-2-sulfonamide?

5-Chlorothiophene-2-sulfonamide has molecular formula C4H4ClNO2S2 and molecular weight 197.663 g/mol.

Is 5-Chlorothiophene-2-sulfonamide hazardous?

5-Chlorothiophene-2-sulfonamide has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 5-Chlorothiophene-2-sulfonamide?

For 5-Chlorothiophene-2-sulfonamide, Upstream Products: 5-Chlorothiophene-2-sulfonyl chloride, 2-Thiophenesulfonyl chloride; Downstream Products: Ethyl N-[(5-chlorothiophen-2-yl)sulfonyl]carbamate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "5-Chlorothiophene-2-sulfonamide (CAS 53595-66-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-26055-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.