Otenzepad

Also known as: AF-DX 116, 11-[2-[2-(diethylaminomethyl)piperidin-1-yl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, 11-[[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 5,11-dihydro-11-[[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-, Brn 4212983

Otenzepad (CAS 102394-31-0) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C24H31N5O2 and a molecular weight of 421.53500 g/mol. Key properties include a boiling point of 573.2ºC at 760 mmHg, a density of 1.171 g/cm3 and a flash point of 300.5ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 102394-31-0
Jingsj CID: J-24933-2
Molecular Formula: C₂₄H₃₁N₅O₂
Molecular Weight: 421.53500 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	573.2ºC at 760 mmHg
Density	1.171 g/cm3
Flash Point	300.5ºC
Exact Mass	421.24800
PSA	74.23000
LogP	3.21440
Storage Conditions	2-8°C

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Target	640 nM (M2 muscarinic acetylcholine receptor in rabbit peripheral lung), 386 nM (M2 muscarinic acetylcholine receptor in rat heart)[1].
Additional Information	[1]. Bloom JW, et al. Heterogeneity of the M1 muscarinic receptor subtype between peripheral lung and cerebral cortex demonstrated by the selective antagonist AF-DX 116. Life Sci. 1987 Jul 27;41(4):491-6. [2]. Packard MG, et al. Post-training injection of the acetylcholine M2 receptor antagonist AF-DX 116 improves memory. Brain Res. 1990 Jul 30;524(1):72-6. [3]. Kopf SR, et al. AF-DX 116, a presynaptic muscarinic receptor antagonist, potentiates the effects of glucose and reverses the effects of insulin on memory. Neurobiol Learn Mem. 1998 Nov;70(3):305-13.

Target

640 nM (M2 muscarinic acetylcholine receptor in rabbit peripheral lung), 386 nM (M2 muscarinic acetylcholine receptor in rat heart)[1].

Additional Information

[1]. Bloom JW, et al. Heterogeneity of the M1 muscarinic receptor subtype between peripheral lung and cerebral cortex demonstrated by the selective antagonist AF-DX 116. Life Sci. 1987 Jul 27;41(4):491-6. [2]. Packard MG, et al. Post-training injection of the acetylcholine M2 receptor antagonist AF-DX 116 improves memory. Brain Res. 1990 Jul 30;524(1):72-6. [3]. Kopf SR, et al. AF-DX 116, a presynaptic muscarinic receptor antagonist, potentiates the effects of glucose and reverses the effects of insulin on memory. Neurobiol Learn Mem. 1998 Nov;70(3):305-13.

Frequently Asked Questions

What is the CAS number of Otenzepad?

The CAS number of Otenzepad is 102394-31-0.

What are the molecular formula and molecular weight of Otenzepad?

Otenzepad has molecular formula C24H31N5O2 and molecular weight 421.53500 g/mol.

Is Otenzepad hazardous?

Otenzepad has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Otenzepad?

For Otenzepad, Upstream Products: 5,11-Dihydro-11-(2-chloroacetyl)-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Otenzepad (CAS 102394-31-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-24933-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.