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2-Chloro-1-(4-fluorophenyl)ethan-1-one

Also known as: 2-Chloro-4'-fluoroacetophenone, 4-Fluorophenacyl chloride, 2-Chloro-1-(4-fluorophenyl)ethanone, α-Chloro-4-fluoroacetophenone, p-Fluorophenacyl chloride, ω-Chloro-4-fluoroacetophenone, 2-Chloro-1-(4-fluorophenyl)ethan-1-one

2-Chloro-1-(4-fluorophenyl)ethan-1-one (CAS 456-04-2) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C8H6ClFO and a molecular weight of 172.584 g/mol. Key properties include a melting point of 47-50 °C(lit.), a boiling point of 247.0±15.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 103.2±20.4 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
456-04-2
Jingsj CID
J-24747-2
Molecular Formula
C8H6ClFO
Molecular Weight
172.584 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point47-50 °C(lit.)
Boiling Point247.0±15.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point103.2±20.4 °C
Exact Mass172.009125
PSA17.07000
LogP1.90
Vapor Pressure0.0±0.5 mmHg at 25°C
Refractive Index1.514

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2914700090
SummaryHS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 2-Chloro-1-(4-fluorophenyl)ethan-1-one?

The CAS number of 2-Chloro-1-(4-fluorophenyl)ethan-1-one is 456-04-2.

What are the molecular formula and molecular weight of 2-Chloro-1-(4-fluorophenyl)ethan-1-one?

2-Chloro-1-(4-fluorophenyl)ethan-1-one has molecular formula C8H6ClFO and molecular weight 172.584 g/mol.

Is 2-Chloro-1-(4-fluorophenyl)ethan-1-one hazardous?

2-Chloro-1-(4-fluorophenyl)ethan-1-one has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 2-Chloro-1-(4-fluorophenyl)ethan-1-one?

For 2-Chloro-1-(4-fluorophenyl)ethan-1-one, Upstream Products: 4'-Fluoroacetophenone, Fluorobenzene, Chloroacetyl chloride; Downstream Products: 1,2-Bis(4-fluorophenyl)ethanone, 3-(4-Fluorophenyl)-1-isopropyl-1H-indole, 2-(4-fluorophenyl)-2-oxoethyl acetate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-Chloro-1-(4-fluorophenyl)ethan-1-one (CAS 456-04-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-24747-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.