Piperlongumine

Also known as: Piplartine, PIPLARTINE, Piperlongumin, PIPERLONGUMIN, Piperlongumine, PPLGM, 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-2(1H)-pyridinone, (E)-Piplartine, 1-[(2E)-3-(3,4,5-Trimethoxyphenyl)-2-propenoyl]-5,6-dihydro-2(1H)-pyridinone, 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-5,6-dihydropyridin-2(1H)-one, 2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-

Piperlongumine (CAS 20069-09-4) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C17H19NO5 and a molecular weight of 317.336 g/mol. Key properties include a melting point of 124ºC, a boiling point of 475.6±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 241.4±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 20069-09-4
Jingsj CID: J-2360-9
Molecular Formula: C₁₇H₁₉NO₅
Molecular Weight: 317.336 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	124ºC
Boiling Point	475.6±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	241.4±28.7 °C
Exact Mass	317.126312
PSA	65.07000
LogP	2.34
Appearance	white to beige
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.581
Storage Conditions	2-8°C
Additional Property	DMSO: ≥5mg/mL at warmed to 60°C

Activity & Biological Data

Target	ERK1 ERK2
Additional Information	[1]. Karki K, et al. Piperlongumine Induces Reactive Oxygen Species (ROS)-Dependent Downregulation of Specificity Protein Transcription Factors. [2]. Wu X, e,t al. Piperlongumine inhibits angiotensin II-induced extracellular matrix expression in cardiac fibroblasts. J Cell Biochem. 2018 Dec;119(12):10358-10364

Customs & Trade Information

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Piperlongumine?

The CAS number of Piperlongumine is 20069-09-4.

What are the molecular formula and molecular weight of Piperlongumine?

Piperlongumine has molecular formula C17H19NO5 and molecular weight 317.336 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Piperlongumine (CAS 20069-09-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2360-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.