CA-074 methyl ester

Also known as: CA-074 Me, CA-074 methyl ester, L-trans-Epoxysuccinyl-Ile-Pro-OMe propylamide, methyl (2S)-1-[(2S)-3-methyl-2-[[(2S,3S)-3-(propylcarbamoyl)oxirane-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carboxylate, N-[(2S,3S)-3-(propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline methyl ester

CA-074 methyl ester (CAS 147859-80-1) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C19H31N3O6 and a molecular weight of 397.46600 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 147859-80-1
Jingsj CID: J-23457-1
Molecular Formula: C₁₉H₃₁N₃O₆
Molecular Weight: 397.46600 g/mol
Category: Esters
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	397.22100
PSA	117.34000
LogP	0.69460

Activity & Biological Data

Additional Information	[1]. Xu Y, et al. Protective mechanisms of CA074-me (other than cathepsin-B inhibition) against programmed necrosis induced by global cerebral ischemia/reperfusion injury in rats. Brain Res Bull. 2016 Jan;120:97-105. [2]. Patel N, et al. CA-074Me compound inhibits osteoclastogenesis via suppression of the NFATc1 and c-FOS signaling pathways. J Orthop Res. 2015 Oct;33(10):1474-86. [3]. Zhang L, et al. Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis. Lab Invest. 2015 Jan;95(1):65-77.

Additional Information

[1]. Xu Y, et al. Protective mechanisms of CA074-me (other than cathepsin-B inhibition) against programmed necrosis induced by global cerebral ischemia/reperfusion injury in rats. Brain Res Bull. 2016 Jan;120:97-105. [2]. Patel N, et al. CA-074Me compound inhibits osteoclastogenesis via suppression of the NFATc1 and c-FOS signaling pathways. J Orthop Res. 2015 Oct;33(10):1474-86. [3]. Zhang L, et al. Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis. Lab Invest. 2015 Jan;95(1):65-77.

Frequently Asked Questions

What is the CAS number of CA-074 methyl ester?

The CAS number of CA-074 methyl ester is 147859-80-1.

What are the molecular formula and molecular weight of CA-074 methyl ester?

CA-074 methyl ester has molecular formula C19H31N3O6 and molecular weight 397.46600 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "CA-074 methyl ester (CAS 147859-80-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-23457-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.