2-Hydroxyestrone

Also known as: Catecholestrone, 2-OHE1, Estra-1,3,5(10)-trien-2,3-diol-17-one, 1,3,5(10)-Estratriene-2,3-diol-17-one, 2,3-Dihydroxy-1,3,5(10)-estratrien-17-one, 2,3-Dihydroxyestra-1,3,5(10)-trien-17-one

2-Hydroxyestrone (CAS 362-06-1) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C18H22O3 and a molecular weight of 286.36500 g/mol. Key properties include a melting point of 199-201ºC, a boiling point of 481.3ºC at 760 mmHg, a density of 1.241g/cm3 and a flash point of 259ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 362-06-1
Jingsj CID: J-23080-8
Molecular Formula: C₁₈H₂₂O₃
Molecular Weight: 286.36500 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	199-201ºC
Boiling Point	481.3ºC at 760 mmHg
Density	1.241g/cm3
Flash Point	259ºC
Exact Mass	286.15700
PSA	57.53000
LogP	3.52300
Refractive Index	1.609
Storage Conditions	2-8°C

Activity & Biological Data

Target	Human Endogenous Metabolite Estrogen receptor
Additional Information	[1]. H L Bradlow, et al. 2-Hydroxyestrone: the 'good' estrogen. J Endocrinol. 1996 Sep;150 Suppl:S259-65. [2]. J Schneider, et al. Antiestrogen action of 2-Hydroxyestrone on MCF-7 human breast cancer cells. J Biol Chem. 1984 Apr 25;259(8):4840-5. [3]. M Nakagomi, et al. Quantitation of catechol estrogens and their N-acetylcysteine conjugates in urine of rats and hamsters. Chem Res Toxicol. 2000 Dec;13(12):1208-13.

Target

Human Endogenous Metabolite Estrogen receptor

Additional Information

[1]. H L Bradlow, et al. 2-Hydroxyestrone: the 'good' estrogen. J Endocrinol. 1996 Sep;150 Suppl:S259-65. [2]. J Schneider, et al. Antiestrogen action of 2-Hydroxyestrone on MCF-7 human breast cancer cells. J Biol Chem. 1984 Apr 25;259(8):4840-5. [3]. M Nakagomi, et al. Quantitation of catechol estrogens and their N-acetylcysteine conjugates in urine of rats and hamsters. Chem Res Toxicol. 2000 Dec;13(12):1208-13.

Frequently Asked Questions

What is the CAS number of 2-Hydroxyestrone?

The CAS number of 2-Hydroxyestrone is 362-06-1.

What are the molecular formula and molecular weight of 2-Hydroxyestrone?

2-Hydroxyestrone has molecular formula C18H22O3 and molecular weight 286.36500 g/mol.

What are the upstream and downstream products of 2-Hydroxyestrone?

For 2-Hydroxyestrone, Upstream Products: Estrone, 19-Nor-4-androstene-3,17-dione, 2-Methoxyestrone; Downstream Products: 2-Methoxyestrone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "2-Hydroxyestrone (CAS 362-06-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-23080-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.