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5-Aminofluorescein

Also known as: Fluoresceinamine, Fluoresceinamine isomer I, Fluoresceinamine, Isomer 1, 4-Aminofluorescein, 5-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one, 5-Aminofluorescein (isomer I), 5-amino-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid, 5-amino-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one, 6-amino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one, 1-Aminofluorescein, 1-Fluoresceinamine, AMINOFLUORESCEIN, EINECS 222-043-6, MFCD00005052, Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 5-amino-3',6'-dihydroxy-

5-Aminofluorescein (CAS 3326-34-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H13NO5 and a molecular weight of 347.321 g/mol. Key properties include a melting point of 223ºC, a boiling point of 695.3±55.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 374.3±31.5 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
3326-34-9
Jingsj CID
J-22998-1
Molecular Formula
C20H13NO5
Molecular Weight
347.321 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point223ºC
Boiling Point695.3±55.0 °C at 760 mmHg
Density1.6±0.1 g/cm3
Flash Point374.3±31.5 °C
Exact Mass347.079376
PSA102.01000
LogP1.80
Vapor Pressure0.0±2.3 mmHg at 25°C
Refractive Index1.820

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Ding R, et al. Pharmacokinetics of 5-aminofluorescein-albumin, a novel fluorescence marker of brain tumors during surgery. J Clin Pharmacol. 2011 May;51(5):672-8. [2]. Miao R, et al. Facile method for modification of the silicon nanowires and its application in fabrication of pH-sensitive chips. ACS Appl Mater Interfaces. 2013 Mar 13;5(5):1741-6. [3]. Wang T, et al. Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein. J Am Chem Soc. 2015 Nov 4;137(43):13736-9. [4]. Shan L, et al. Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy. Int J Nanomedicine. 2015 Sep 1;10:5571-91.

Customs & Trade Information

HS Code2921199090
Summary2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 5-Aminofluorescein?

The CAS number of 5-Aminofluorescein is 3326-34-9.

What are the molecular formula and molecular weight of 5-Aminofluorescein?

5-Aminofluorescein has molecular formula C20H13NO5 and molecular weight 347.321 g/mol.

Is 5-Aminofluorescein hazardous?

5-Aminofluorescein has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 5-Aminofluorescein?

For 5-Aminofluorescein, Upstream Products: 5-Nitrofluorescein, 4-Nitrophthalic acid, Resorcinol; Downstream Products: Fluorescein isothiocyanate isomer I, Fluorescein-5-maleimide, Fluorescein.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "5-Aminofluorescein (CAS 3326-34-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-22998-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.